Table 1

Prognostic scores and their components

Measured indices Study population and primary outcome AUROC for death or readmission48
AgeBMIComorbidity*Dyspnoea†Airflow obstruction‡Exacerbations§Severe exacerbations¶Smoking statusLength of stayAcuity**ED visits last 6 monthsCOPD specific?Stable-state or exacerbating at inclusionOutpatients or admitted patientsPrimary outcome
ADO5 BothBothDeath0.58
BODEX6 StableOutpatientsDeath0.61
CODEX4††AECOPDMostly admittedDeath or readmission0.67
DOSE7 UnclearOutpatientsHealth status‡‡0.64
LACE8 XN/AAdmittedDeath or readmission0.68§§
  • *Charlson Comorbidity Index.

  • †mMRC dyspnoea score.

  • ‡FEV1 %predicted.

  • §Patient reported AECOPD in previous year.

  • ¶AECOPD in previous year requiring admission or ED attendance.

  • **Elective or emergency admission.

  • ††Uses age-adjusted Charlson Comorbidity Index.

  • ‡‡Measured by the clinical COPD questionnaire.

  • §§30-day death or readmission.

  • AECOPD, acute exacerbation of COPD; AUROC, area under the receiver operating characteristic; BMI, body mass index; ED, emergency department; mMRC, modified Medical Research Council; n/a, not available.