Comparison of change in 6MWD between intention to treat and per protocol analyses for each subgroup
| Mean difference (95% CI) | ||
|---|---|---|
| 9 week follow-up | 6 month follow-up | |
| IPF | ||
| ITT n=29/32 | 31 (−5 to 66) | 0.9 (−36 to 38) |
| PP Completion n=29/15 | 26 (−14 to 67) | −18 (−63 to 26) |
| PP Progression n=29/16 | 55 (13–97) | 15 (−30 to 60) |
| Asbestosis | ||
| ITT n=11/11 | 68 (10 to 124) | 92 (36 to 148) |
| PP Completion n=11/10 | 75 (19 to 132) | 93 (38 to148) |
| PP Progression n=11/10 | 75 (19 to 132) | 93 (38 to148) |
| CTD-ILD | ||
| ITT n=12/11 | 3 (−53 to 60) | 21 (−35 to 77) |
| PP Completion n=12/6 | 14 (−50 to 78) | 38 (−25 to 101) |
| PP Progression n=12/6 | 14 (−50 to 78) | 38 (−25 to 101) |
Values are mean difference (SE). Data are exercise group – control group. n=number of participants in usual care group/exercise training group for the corresponding analysis.
6MWD, six-minute walk distance; CTD, connective tissue disease; ILD, interstitial lung disease; IPF, idiopathic pulmonary fibrosis; ITT, intention to treat; PP, per protocol.