Table 5
Associations with evaluated contacts (of index cases with TB at any site) with active TB
| Characteristics of the index case | Contact diagnosed with active TB | |||
|---|---|---|---|---|
| Yes (row %)* | No* | aOR (95%CI) | p Value | |
| Total | 263 (1.8%) | 14 351 | N/a | N/a |
| UK born | ||||
| Yes | 71 (2.3%) | 2973 | 1.31 (0.86 to 1.99) | 0.41 |
| No, long-term migrant | 159 (1.6%) | 9834 | 1 | |
| No, recent migrant | 33 (2.1%) | 1544 | 1.23 (0.71 to 2.15) | |
| History of drug use | ||||
| Yes | 18 (2.9%) | 612 | 1.06 (0.56 to 2.01) | 0.85 |
| No | 245 (1.8%) | 13 739 | 1 | |
| History of homelessness | ||||
| Yes | 13 (2.6%) | 485 | 0.77 (0.36 to 1.66) | 0.51 |
| No | 250 (1.8%) | 13 866 | 1 | |
| Former prisoner | ||||
| Yes | 9 (2.8%) | 312 | 1.02 (0.37 to 2.84) | 0.96 |
| No | 254 (1.8%) | 14 039 | 1 | |
| Sex | ||||
| Male | 164 (2.0%) | 7884 | 1.35 (0.95 to 1.91) | 0.09 |
| Female | 99 (1.5%) | 6467 | 1 | |
| Ethnicity | ||||
| Indian | 39 (1.2%) | 3130 | 1 | <0.01 |
| Black African | 103 (3.0%) | 3324 | 1.95 (1.17 to 3.26) | |
| White | 32 (1.7%) | 1910 | 0.81 (0.44 to 1.50) | |
| Other | 89 (1.5%) | 5987 | 1.03 (0.63 to 1.67) | |
| Culture | ||||
| Positive | 225 (2.4%) | 9316 | 1 | 0.12 |
| Negative | 71 (0.8%) | 4033 | 0.70 (0.43 to 1.15) | |
| Not done | 7 (0.7%) | 1002 | 0.50 (0.23 to 1.09) | |
| Disease type | ||||
| Non-pulmonary and non-laryngeal | 41 (0.6%) | 6391 | 1 | <0.01 |
| Pulmonary smear-negative | 44 (1.4%) | 3107 | 2.10 (1.20 to 3.69) | |
| Pulmonary smear-positive | 166 (4.3%) | 3696 | 6.71 (4.11 to 11.0) | |
| Pulmonary, smear unknown or laryngeal | 12 (1.0%) | 1157 | 1.39 (0.73 to 2.64) | |
| BCG | ||||
| Not vaccinated | 51 (1.6%) | 3222 | 0.78 (0.51 to 1.18) | 0.28 |
| Vaccinated | 177 (2.0%) | 8502 | 1 | |
| Unknown | 35 (1.3%) | 2627 | 0.73 (0.44 to 1.19) | |
| Clinic case count* (linear, 100 cases/year) |  | s=0.52 | 0.97 (0.68 to 1.40) | 0.89 |
| Age of index case | ||||
| 0–14 years | 25 (5.7%) | 417 | 1 | <0.01 |
| 15 years and over | 238 (1.7%) | 13 934 | 0.25 (0.13 to 0.48) | |
| Notification rate*† (linear, 10 cases/100 000 population/year) |  | s=1.9 | 1.05 (0.95 to 1.17) | 0.32 |
| Age of contact | ||||
| 15 years and over | 151 (1.5%) | 10 133 | 0.55 (0.40 to 0.75) | <0.01 |
| 0–14 years | 112 (2.6%) | 4218 | 1 | |
| Contact screened at clinic | ||||
| Yes | 233 (1.9%) | 12 162 | 1.38 (0.81 to 2.37) | 0.24 |
| No | 30 (1.4%) | 2189 | 1 | |
*Mean and SD presented for continuous variables.
†Notification rate in the year and local authority in which the index case was notified. N=14 614.
aOR, adjusted OR.