Clinical outcomes—intention-to-treat analysis
| Within-group differences from baseline (95% CI) | Between-group differences | |||||
|---|---|---|---|---|---|---|
| Home (n=72) | Centre (n=76) | Home-Centre (95% CI) | ||||
| End rehabilitation | 1 year | End rehabilitation | 1 year | End rehabilitation | 1 year | |
| 6MWD, m | 29.39 (13.78 to 45.01) | −4.74 (−21.94 to 12.47) | 10.82 (−4.52 to 26.16) | 0.41 (−16.34 to 17.15) | 18.57 (−3.32 to 40.71)* | −5.14 (−29.15 to 18.87)† |
| CRQ dyspnoea | 4.24 (2.88 to 5.60) | 1.95 (0.50 to 3.39) | 2.68 (1.38 to 3.99) | 1.90 (0.46 to 3.34) | 1.56 (−0.33 to 3.45)* | 0.05 (−2.00 to 2.10) |
| CRQ fatigue | 2.17 (1.11 to 3.23) | 0.90 (−0.21 to 2.02) | 1.35 (0.33 to 2.36) | 1.18 (0.08 to 2.29) | 0.82 (−0.65 to 2.29)* | −0.28 (−1.86 to 1.29) |
| CRQ emotional | 3.14 (1.47 to 4.80) | 3.08 (1.32 to 4.84) | 2.31 (0.71 to 3.91) | 2.57 (0.81 to 4.32) | 0.83 (−1.50 to 3.14) | 0.52 (−1.97 to 3.00) |
| CRQ mastery | 2.43 (1.39 to 3.46) | 2.12 (1.02 to 3.23) | 2.02 (1.03 to 3.01) | 1.45 (0.35 to 2.56) | 0.41 (−1.03 to 1.84) | 0.67 (−0.90 to 2.23)* |
| PRAISE | 1.09 (−0.69 to 2.87) | 1.73 (−0.22 to 3.68) | −0.16 (−1.87 to 1.56) | 2.38 (0.45 to 4.31) | 1.25 (−1.23 to 3.72) | −0.65 (−3.40 to 2.10) |
| MMRC | −0.12 (−0.36 to 0.12) | 0.22 (−0.03 to 0.48) | 0.00 (−0.23 to 0.23) | 0.48 (0.23 to 0.74) | −0.12 (−0.45 to 0.21) | −0.26 (−0.62 to 0.10) |
Data are mean and 95% CIs adjusted for baseline values.
No significant difference between groups for any outcome.
*CI exceeds the upper equivalence limit of the minimal important difference and cannot exclude superiority.
†CI exceeds the lower equivalence limit and cannot exclude inferiority.
6MWD, 6 min walk distance; CRQ, Chronic Respiratory Questionnaire; MMRC, modified Medical Research Council scale; PRAISE, Pulmonary Rehabilitation Adapted Index of Self-Efficacy.