Abstract P299 Table 1
Dyspnoea severityLess severeMore severeLess severeMore severe
Treatment comparisonmMRC score < 2mMRC score ≥ 2BDI score
≥6		BDI score
<6
FEV1 AUC0–3, L
T/O 5/5 µg – placebo0.30***
(0.26, 0.34)		0.32***
(0.28, 0.36)		0.32***
(0.29, 0.35)		0.28***
(0.22, 0.35)
T/O 5/5 µg – T0.11***
(0.07, 0.14)		0.11***
(0.07, 0.15)		0.11***
(0.08, 0.14)		0.10**
(0.04, 0.15)
Trough FEV1, L
T/O 5/5 µg – placebo0.16***
(0.13, 0.20)		0.16***
(0.13, 0.20)		0.18***
(0.15, 0.21)		0.12***
(0.07, 0.18)
T/O 5/5 µg – T0.05*
(0.01, 0.08)		0.02
(−0.01, 0.06)		0.040**
(0.01, 0.07)		0.01
(−0.04, 0.06)
SGRQ total score
T/O 5/5 µg – placebo−4.20***
(−6.11, −2.29)		−5.11***
(−7.24, −2.97)		−4.78***
(−6.33, −3.23)		−4.38
(−8.95, 0.19)
T/O 5/5 µg – T−0.71
(−2.57, 1.16)		−3.44**
(−5.47, −1.41)		−1.87*
(−3.43, −0.32)		−2.96*
(−5.84, −0.09)

  • Adjusted mean (95% confidence interval) ***p <0.0001; **p <0.01; *p <0.05