showing mean baseline lung function and annual decline. All values are expressed as percentages and based on predicted values for age, weight and sex (percentage predicted values). Ranges are in brackets.
| Baseline FEV1 | FEV1 annual change | Baseline FVC | FVC annual change | Baseline VC | VC annual change | Baseline TLC | TLC annual change | Baseline KCO | KCO annual change | |
|---|---|---|---|---|---|---|---|---|---|---|
| Whole population (n = 48) | 89.4 (51.0–136) | −0.2 | 96.7 (47.0–139.0) | −1.0 | 94.9 (51.0–134) | −0.7 | 77.5 (44.0–121.0) | −2.0 | 94.6 (49.0-135–.0) | −2.5 |
| Lifelong non smoker (n = 6) | 105.8 (77.0–36.0) | −1.2 | 108.7 (91.0–139.0) | −2.5 | 105.0 (94.0–134.0) | −2.32 | 83.2 (64.0–100.0) | −4.9 | 106.5 (90.0-130.0) | −3.9 |
| Ex smoker <20 pack years (n = 13) | 91.9 (51.0–133.0) | −1.8 | 93.8 (54.0–133.0) | −2.8 | 90.4 (51.0–127) | −2.61 | 70.1 (44.0–88.0) | −1.1 | 109.2 (78.0-135.0) | −7.2 |
| Ex smoker 20–40 pack years (n = 16) | 96.0 (69.0–125.0) | 0.0 | 103.8 (67.0–134.0) | −1.2 | 99.9 (65.0–125.0) | −0.2 | 83.9 (53.0–121.0) | −3.5 | 95.6 (70.0-147.0) | −1.0 |
| Ex smoker >40 pack years (n = 9) | 67.5 (53.0–98.0) | +1.0 | 80.3 (47.0–107.0) | +1.0 | 81.9 (57.0–108.0) | +0.7 | 70.8 (48.0–98.0) | +1.9 | 78.4 (57.0-112.0) | −1.4 |
| Current smoker (n = 4) >40 pack years | 80.0 (72.0–86.0) | +1.01 | 97.0 (84.0–109.0) | +1.75 | 102.0 (88.0–115.0) | +0.18 | Not calculated | Not calculated | 68.5 (49.0-109.0) | −2.39 |