Demographic and clinical characteristics of children in the study
| IGRA status | BCG status | ||||
|---|---|---|---|---|---|
| Characteristic | IGRA negative (%) | IGRA positive (%) | BCG unvaccinated (%) | BCG vaccinated (%) | Total (%) |
| Total | 314 (100) | 108 (100) | 122 (100) | 300 (100) | 422 (100) |
| Gender | |||||
| Male | 164 (52.2) | 52 (48.2) | 64 (52.5) | 152 (50.7) | 216 (51.2) |
| Female | 150 (47.8) | 56 (51.9) | 58 (47.5) | 148 (49.3) | 206 (48.8) |
| Median age in months (IQR) | 60 (25–104) | 94 (61–136) | 71 (37–118) | 68 (30–110) | 69 (32–113) |
| Ethnicity | |||||
| White | 69 (22.0) | 36 (33.3) | 84 (68.9) | 21 (7.0) | 105 (24.9) |
| Indian | 38 (12.1) | 10 (9.3) | 3 (2.5) | 45 (15.0) | 48 (11.4) |
| Pakistani | 60 (19.1) | 18 (16.7) | 8 (6.6) | 70 (23.3) | 78 (18.5) |
| Bangladeshi | 34 (10.8) | 4 (3.7) | 2 (1.6) | 36 (12.0) | 38 (9.0) |
| Black Caribbean | 2 (0.6) | 0 | 0 | 2 (0.7) | 2 (0.5) |
| Black African | 68 (21.7) | 27 (25.0) | 12 (9.8) | 83 (27.7) | 95 (22.5) |
| Black Other | 8 (2.6) | 6 (5.6) | 5 (4.1) | 9 (3.0) | 14 (3.3) |
| Chinese | 1 (0.3) | 0 | 0 | 1 (0.3) | 1 (0.2) |
| Mixed/other | 34 (10.8) | 7 (6.5) | 8 (6.6) | 33 (11.0) | 41 (9.7) |
| HIV status* | |||||
| Negative | 280 (89.2) | 90 (83.3) | 100 (82.0) | 270 (90) | 370 (87.7) |
| Positive | 0 | 0 | 0 | 0 | 0 |
| Not tested | 34 (10.8) | 18 (16.7) | 22 (18.0) | 30 (10) | 52 (12.3) |
| Born in the UK | |||||
| No | 36 (11.5) | 25 (23.2) | 12 (9.8) | 49 (16.3) | 61 (14.5) |
| Yes | 278 (88.5) | 83 (76.9) | 110 (90.2) | 251 (83.7) | 361 (85.6) |
| Type of IGRA | |||||
| QuantiFERON-TB Gold | 190 (60.7) | 71 (65.7) | 84 (68.9) | 177 (59.2) | 261 (62.0) |
| T-SPOT.TB | 124 (39.3) | 37 (34.3) | 38 (31.2) | 122 (40.8) | 161 (38.0) |
*HIV status was known in 370 children. No children were known to be HIV positive.
IGRA, interferon γ release assay.