Comparisons of demographic characteristics between UK and US data
| USA | UK | USA–UK difference (95% CI)* | p Value | |||
|---|---|---|---|---|---|---|
| N | 24 835 | 7933 | ||||
| Number of centres providing data in 2010 | 237 | 132 | ||||
| [n] | [n] | |||||
| Age (years) | 24 835 | 7933 | ||||
| Median (IQR) | 16.2 (8.3–25.6) | 17.9 (9.3–27.0) | −1.2 (−1.50 to −0.90) | <0.001 | ||
| ≥16 years; n (%) | 12 631 (50.9) | 4421 (55.7) | −4.9% (−6.1% to −3.6%) | <0.001 | ||
| ≥18 years; n (%) | 11 058 (44.5) | 3965 (50.0) | −5.5% (−6.7% to −4.2%) | <0.001 | ||
| Sex | 24 835 | 7933 | ||||
| Male; n (%) | 12 819 (51.6) | 4214 (53.1) | −1.5% (−0.2% to −2.8%) | 0.020 | ||
| Race/ethnicity | ||||||
| Asian; n (%) | 24 835 | 92 (0.4%) | 7837 | 198 (2.5%) | <0.001 | |
| Black; n (%) | 842 (3.4%) | 29 (0.4%) | ||||
| White†; n (%) | 21 594 (87.0%) | 7580 (96.7%) | ||||
| Other‡; n (%) | 2307 (9.3%) | 30 (0.4%) | ||||
| Age at diagnosis (years) | ||||||
| Median (min–max) | 24 727 | 0.4 (0–78.5) | 7856 | 0.3 (0–79.2) | −0.8% (0.2% to 1.4%) | <0.001 |
| <3 months; n (%) | 10 209 (41.3) | 3682 (46.9) | <0.001 | |||
| 3–6 months; n (%) | 2743 (11.1) | 862 (11.0) | (trend) | |||
| 6–12 months; n (%) | 2842 (11.5) | 649 (8.3) | 0.007 | |||
| 12 months–3 years; n (%) | 3251 (13.2) | 1047 (13.3) | ||||
| ≥3 years; n (%) | 5682 (23.0) | 1616 (20.6) | ||||
| ≥18 years; n (%) | 1280 (5.2) | 469 (6.0) | ||||
Results are presented as means (SD), medians (IQR) or n (%). [n] refers to the number of non-missing observations for each given variable in each country/subgroup.
*Where medians are used, differences between the groups are presented as the median difference between values sampled from two groups. This difference is not strictly equal to the difference between the two medians.
†For the purposes of this analysis (to facilitate comparisons between the USA and the UK), white was defined as non-Hispanic white patients.
‡For the purposes of this analysis, subjects with Hispanic ethnicity were included in the ‘other’ category.