Tidal breathing and dynamic compliance
| Parameter | Normal group, seated | Obese group, seated | p Value | Normal group, supine | Obese group, supine | p Value |
|---|---|---|---|---|---|---|
| Vt (L) | 0.64 (0.14) | 0.63 (0.10) | 0.584 | 0.61 (0.13) | 0.67 (0.12) | 0.317 |
| Vt (%predTLC) | 9.3 (1.4) | 11.5 (2.1) | 0.017 | 9.6 (1.8) | 12.2 (2.8) | 0.031 |
| Cdyn (L/cm H2O) | 0.194 (0.070) | 0.142 (0.049) | 0.087 | 0.135 (0.037)* | 0.105 (0.024)* | 0.057 |
| Cdyn (%predTLC/cm H2O) | 3.0 (1.0) | 2.6 (1.0) | 0.398 | 2.1 (0.4)* | 2.0 (0.7)** | 0.545 |
| Poes, ee (cm H2O) | −2.0 (3.5) | 5.2 (6.9) | 0.013 | 5.4 (3.1)*** | 14.0 (8.0)** | 0.008 |
| Pgas, ee (cm H2O) | 12.1 (6.2) | 19.1 (4.7) | 0.015 | 7.1 (2.6)* | 14.3 (5.7)* | 0.003 |
| Pdi, ee (cm H2O) | 14.1 (5.3) | 13.9 (5.1) | 0.933 | 1.7 (2.8)*** | 0.2 (5.3)*** | 0.461 |
| PL, ee (cm H2O) | 2.9 (1.4) | −4.7 (5.0) | <0.001 | −4.6 (2.5)*** | −11.6 (5.0)*** | 0.002 |
Lung volumes, dynamic compliance and end-expiratory pressures at FRC in the thoracic and abdominal compartment for obese and normal subjects, seated and supine.
*p<0.05, **p<0.01, ***p<0.001 for the comparison of associated changes with posture
cdyn, dynamic compliance; FRC, functional residual capacity; Pdi, ee, transdiaphragmatic pressure at end-expiration; Pgas, ee, gastric pressure at end-expiration; PL, ee, transpulmonary pressure at end-expiration; Poes, ee, oesophageal pressure at end-expiration; TLC, total lung capacity; Vt, tidal volume.