Baseline, 6 month, mean change and treatment effect data for all outcomes (excluding patients with CRP values >8 at baseline or follow-up)
| Standard care | CPAP | Treatment effect (95% CI) | p Value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Baseline | 6 months | Mean change (SD) | N | Baseline | 6 months | Mean change (SD) | |||
| Highly sensitive CRP (mg/L) | 113 | 1.56 (0.84–3.48) | 1.66 (0.87–3.44) | +0.03 (1.78) | 125 | 1.86 (0.84–3.32) | 1.49 (0.82–2.75) | −0.19 (1.56) | −0.20 (−0.59 to +0.18) | 0.30 |
| Interleukin 6 (pg/mL) | 111 | 0.48 (0.19–0.92) | 0.58 (0.26–1.09) | +0.14 (0.61) | 125 | 0.44 (0.24–0.79) | 0.52 (0.22–0.96) | +0.11 (0.45) | −0.04 (−0.17 to +0.10) | 0.62 |
| Interleukin 10 (pg/mL) | 111 | 0.59 (0.33–1.02) | 0.70 (0.39–1.21) | +0.11 (1.22) | 125 | 0.61 (0.29–1.01) | 0.60 (0.33–1.04) | +0.48 (2.50) | +0.35 (−0.12 to +0.83) | 0.14 |
| Tumour necrosis factor (pg/mL) | 113 | 1.56 (0.84–3.48) | 1.66 (0.87–3.44) | +0.03 (1.78) | 125 | 1.86 (0.84–3.32) | 1.49 (0.82–2.75) | −0.19 (1.56) | +0.05 (−0.05 to +0.15) | 0.37 |
Baseline and 6 month values are summarised by median (25th–75th centiles).
CRP, C reactive protein.