Between-group differences between baseline and after intervention for peak oxygen uptake, pulmonary function, muscular strength, body composition and functional capacity
| Outcome variable | Baseline | After intervention | Between-group difference | |||
|---|---|---|---|---|---|---|
| Exercise group | Control | Exercise group | Control | Difference (95% CI) | p Value | |
| Peak oxygen uptake (L/min) | 1.38±0.37 | 1.28±0.46 | 1.76±0.49 | 1.39±0.51 | 0.26 (0.11 to 0.42) | 0.005 |
| Peak oxygen uptake (mL/kg/min) | 19.2±5.1 | 18.1±5.5 | 23.3±5.5 | 19.0±6.0 | 3.4 (1.3 to 5.5) | 0.002 |
| FEV1 (% of predicted value) | 71.1±16.3 | 72.3±18.5 | 77.9±16.2 | 78.4±22.8 | 0.6 (−4.2 to 5.4) | 0.738 |
| MVV (% of predicted value) | 78.6±22.0 | 78.9±22.1 | 83.2±22.4 | 79.8±21.8 | 3.7 (−2.6 to 10.1) | 0.064 |
| Tlco (% of predicted value) | 67.8±19.2 | 63.4±16.8 | 73.7±16.5 | 64.9±18.2 | 5.2 (0.0 to 10.4) | 0.007 |
| Leg press, maximum (kg)* | 131.9±45.7 | 131.6±48.5 | 159.3±48.4 | 129.5±39.5 | 29.5 (15.2 to 43.7) | <0.001 |
| Hand grip, maximum (kg)* | 34.2±11.5 | 32.9±8.4 | 36.6±11.4 | 33.3±8.6 | 2.1 (0.0 to 4.1) | 0.056 |
| BMI | 24.9±4.9 | 24.4±5.3 | 25.6±4.8 | 24.9±4.7 | 0.2 (−0.6 to 1.1) | 0.034 |
| Total muscle mass (kg) | 46.43±11.63 | 46.32±10.34 | 47.91±13.75 | 46.45±10.10 | 1.36 (0.32 to 2.40) | 0.012 |
| Chair stand (times) | 11.4±2.1 | 11.4±3.5 | 14.3±2.8 | 12.2±3.0 | 2.1 (0.8 to 3.3) | <0.001 |
| Stair run (number of steps) | 30.5±8.3 | 28.3±9.9 | 37.0±9.5 | 30.8±9.3 | 4.3 (1.6 to 7.1) | 0.002 |
Data are presented as mean±SD.
*To convert leg and hand press values to lb, divide by 0.45359.
1RM, one-repetition maximum; BMI, body mass index; FEV1, forced expiratory volume in 1 s. FVC, forced vital capacity; MVV, maximal voluntary ventilation; Tlco, carbon monoxide transfer factor.