Patient characteristics.
| Characteristic | VAP (N=53) | Non-VAP (N=97) | p Value |
|---|---|---|---|
| Age (years) | 56.3±17.7 | 55.2±17.3 | 0.48 |
| Male—n (%) | 42 (79.2) | 69 (71.1) | 0.28 |
| Time from ICU admission to consent (days)—median (IQR)* | 5 (4–8) | 7 (4–11) | 0.43 |
| APACHE II score on admission | 17.3±6.0 | 19.1±7.8 | 0.15 |
| Surgical admission—n (%) | 31 (58.5) | 41 (42.3) | 0.06 |
| Medical admission—n (%) | 22 (41.5) | 56 (57.7) | 0.06 |
| Hospital mortality—n (%)† | 19 (38.8) | 31 (33) | 0.49 |
| Hospital LOS (days)—median (IQR)‡ | 39 (25–65) | 36 (20–51) | 0.26 |
| ICU LOS (days)—median (IQR)§ | 17 (14–34) | 17 (11–31) | 0.21 |
| Renal replacement therapy—n (%)¶ | 5 (9.4) | 12 (12.5) | 0.57 |
| Vasopressors—n (%)† | 12 (23.1) | 35 (36.5) | 0.10 |
| ARDS criteria—n (%)** | 8 (16) | 19 (21.3) | 0.44 |
| Receipt of corticosteroids—n (%)* | 7 (13.2) | 21 (22.8) | 0.16 |
| Antibiotics at time of BAL—n (%) | 30 (56.6) | 80 (82.5) | 0.001 |
| New antibiotics started in 72 hours before BAL—n (%) | 8 (15.1) | 27 (27.8) | 0.08 |
| Antibiotic days in the 7 days post BAL—median (IQR)* | 7 (5–7) | 6.5 (4–7) | 0.43 |
| Antibiotic-free days (AFD) in the 7 days following BAL—median (IQR)* | 0 (0–2) | 0 (0–2.3) | 0.21 |
Plus/minus values are mean±SD.
Data missing for: *5 patients; †7 patients; ‡21 patients; §2 patients; ¶1 patient and **11 patients.
APACHE II, Acute Physiology and Chronic Health Evaluation II; ARDS, acute respiratory distress syndrome; BAL, bronchoalveolar lavage; ICU, intensive care unit; LOS, length of stay; VAP, ventilator-acquired pneumonia.