Treatment comparisons between the USA and the UK
| USA | UK | USA–UK difference (95% CI) | p Value | |||
|---|---|---|---|---|---|---|
| Treatment | Total n | n (%) | Total n | n (%) | ||
| Hypertonic saline; n (%) | ||||||
| <18 years | 13 412 | 5489 (40.9) | 390 738 | 327 (8.4) | 32.6 (31.4 to 33.8) | <0.001 |
| ≥18 years | 10 803 | 5594 (51.8) | 70 | 571 (14.8) | 37.0 (35.6 to 38.5) | <0.001 |
| Any nebulised antibiotic, n (%) | ||||||
| <18 years | 13 412 | 6000 (44.7) | 3907 | 1674 (42.9) | 1.9 (0.1 to 3.7) | 0.036 |
| ≥18 years | 10 803 | 7079 (65.5) | 3870 | 2396 (61.9) | 3.6 (1.8 to 5.4) | <0.001 |
| rhDNase; n (%) | ||||||
| <18 years | 13 412 | 10 360 (77.2) | 3907 | 1382 (35.4) | 41.9 (40.2 to 43.5) | <0.001 |
| ≥18 years | 10 803 | 8126 (75.2) | 3870 | 2009 (51.9) | 23.3 (21.5 to 25.1) | <0.001 |
| Macrolides, n (%) | ||||||
| <18 years | 13 412 | 4505 (33.6) | 3907 | 942 (24.1) | 9.5 (7.9 to 11.0) | <0.001 |
| ≥18 years | 10 803 | 7061 (65.4) | 3870 | 2373 (61.3) | 4.0 (2.3 to 5.8) | <0.001 |