Relative mean abundances of bacterial families in lower and upper airways
| Lower airways | Upper airways | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Relative mean abundance in % | Relative mean abundance in % | |||||||||||
| Bacterial families | IIP (n=5) | non-IIP (n=6) | Sarcoidosis (n=7) | PCP (n=6) | Control (n=9) | p Value* | IIP (n=5) | non-IIP (n=6) | Sarcoidosis (n=7) | PCP (n=6) | Control (n=9) | p Value* |
| Moraxellaceae | 0.1 | 0.1 | 0.0 | 0.4 | 1.8 | 0.068 | 2.2 | 0.0 | 0.0 | 0.0 | 1.2 | 0.456 |
| Comamonadaceae | 0.1 | 0.8 | 0.2 | 1.3 | 0.4 | 0.274 | 0.8 | 0.0 | 0.6 | 0.0 | 0.6 | 0.727 |
| Cellulomonadaceae | 0.0 | 0.0 | 0.0 | 11.8 | 0.0 | 0.357 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.000 |
| Aerococcaceae | 0.8 | 1.3 | 0.6 | 0.8 | 0.5 | 0.488 | 0.4 | 3.0 | 0.9 | 3.1 | 1.2 | 0.428 |
| Rhizobiaceae | 0.1 | 1.4 | 0.4 | 1.4 | 0.4 | 0.191 | 0.2 | 0.1 | 0.4 | 0.0 | 1.2 | 0.462 |
| Lactobacillaceae | 0.1 | 0.0 | 0.0 | 0.0 | 1.3 | 0.560 | 0.8 | 0.0 | 0.1 | 0.0 | 0.8 | 0.413 |
| Nocardiaceae | 0.4 | 1.2 | 0.4 | 1.8 | 0.1 | 0.058 | 0.0 | 0.2 | 0.5 | 0.1 | 0.1 | 0.626 |
| Capnocytophagaceae | 0.1 | 2.2 | 0.6 | 3.1 | 0.9 | 0.239 | 1.9 | 0.4 | 1.0 | 2.2 | 0.7 | 0.522 |
| Microbacteriaceae | 0.4 | 1.4 | 0.5 | 1.2 | 0.1 | 0.061 | 0.1 | 0.1 | 1.0 | 0.2 | 0.1 | 0.585 |
| Sphingomonadaceae | 0.1 | 0.5 | 0.2 | 0.4 | 0.2 | 0.388 | 0.1 | 0.2 | 0.1 | 0.0 | 0.3 | 0.509 |
| Flavobacteriaceae | 1.1 | 4.3 | 1.3 | 4.7 | 0.4 | 0.036 | 0.2 | 0.5 | 1.2 | 8.1 | 0.2 | 0.048 |
| Peptostreptococcaceae | 1.3 | 1.0 | 1.0 | 0.7 | 1.1 | 0.931 | 0.9 | 0.6 | 1.6 | 0.3 | 0.3 | 0.184 |
| Fusobacteriaceae | 1.9 | 7.3 | 5.9 | 2.0 | 6.4 | 0.282 | 2.1 | 3.5 | 6.3 | 11.8 | 6.2 | 0.442 |
| Staphylococcaceae | 0.0 | 1.5 | 1.0 | 5.9 | 0.5 | 0.313 | 0.4 | 2.4 | 3.2 | 7.8 | 0.7 | 0.355 |
| Porphyromonadaceae | 2.8 | 5.3 | 4.1 | 11.5 | 2.8 | 0.586 | 4.1 | 2.3 | 8.1 | 5.7 | 2.0 | 0.147 |
| Pasteurellaceae | 19.0 | 4.0 | 2.5 | 4.3 | 1.1 | 0.345 | 2.0 | 3.4 | 2.7 | 39.3 | 1.4 | 0.412 |
| Neisseriaceae | 16.2 | 4.2 | 4.7 | 9.2 | 6.6 | 0.686 | 22.5 | 1.1 | 6.1 | 10.5 | 4.5 | 0.281 |
| Acidaminococcaceae | 4.7 | 15.0 | 12.1 | 5.1 | 6.2 | 0.114 | 9.3 | 10.2 | 6.6 | 10.1 | 5.3 | 0.771 |
| Streptococcaceae | 4.3 | 10.3 | 21.6 | 4.2 | 17.4 | 0.380 | 12.6 | 10.9 | 9.6 | 7.6 | 22.0 | 0.090 |
| Prevotellaceae | 39.3 | 26.8 | 37.0 | 24.7 | 42.0 | 0.760 | 32.3 | 33.9 | 35.1 | 24.8 | 40.9 | 0.767 |
*p Values derived by ordinary one-way analysis of variance are indicated. p<0.05 is considered as being significant indicating a difference between the five groups.
IIP, idiopathic interstitial pneumonia; non-IIP, non-idiopathic interstitial pneumonia; PCP, Pneumocystis pneumonia.