Unadjusted associations between BMI, age, other variables and development of third trimester OSA (n=94)
| OR for 3rd trimester OSA (95% CI) | p Value | |
|---|---|---|
| Baseline BMI, 5 kg/m2 | 1.79 (1.17 to 2.74) | 0.007 |
| Third trimester BMI, 5 kg/m2 | 1.97 (1.21 to 3.22) | 0.007 |
| Baseline BMI | 0.070* | |
| Normal | Ref | – |
| Overweight | 2.60 (0.43 to 15.65) | 0.297 |
| Class I obesity | 3.82 (0.66 to 22.00) | 0.133 |
| Class II–III obesity | 8.67 (1.59 to 47.15) | 0.013 |
| Third trimester BMI | 0.043* | |
| Normal | Ref | – |
| Overweight | 0.08 (0.00 to 1.75) | 0.107 |
| Class I obesity | 0.37 (0.03 to 4.90) | 0.451 |
| Class II–III obesity | 1.16 (0.09 to 14.29) | 0.909 |
| Gestational weight gain, kg | 0.94 (0.58 to 1.03) | 0.195 |
| First trimester neck circumference, cm | 1.20 (1.00 to 1.43) | 0.049 |
| Third trimester neck circumference, cm | 1.22 (1.01 to 1.47) | 0.040 |
| Age, 10 years | 2.92 (1.38 to 6.18) | 0.005 |
| Baseline AHI, events/h | 1.30 (0.91 to 1.86) | 0.153 |
| First trimester Epworth score | 1.03 (0.92 to 1.16) | 0.554 |
| Third trimester Epworth score | 1.07 (0.94 to 1.22) | 0.283 |
| Nulliparity (ref multiparity) | 0.67 (0.24 to 1.86) | 0.443 |
| Parity (total number of prior pregnancies) | 1.31 (1.04 to 1.67) | 0.025 |
| White and other ethnicity (ref African–American) | 0.48 (0.13 to 1.83) | 0.283 |
The bold numbers are statistically significant at the <0.05 level.
*Omnibus p value for BMI group differences in the logistic regression model. Pairwise comparisons for subgroups are reported in italics for individual BMI groups, compared to normal BMI.
AHI, Apnoea-Hypopnoea Index; BMI, Body Mass Index; OSA, obstructive sleep apnoea.