Baseline characteristics of patients presenting with acute chest syndrome and a new pulmonary opacity on CT
| At least one complete lung segment consolidation during at least one ACS episode | |||
|---|---|---|---|
| Parameter | No (n=41) | Yes (n=75) | p Value |
| Age, years | 30 [24–40] | 27 [23–32] | 0.04 |
| Male gender | 18 (44%) | 31 (41%) | 0.79 |
| Body mass index, kg/m2 | 21±2 | 21±2 | 0.28 |
| SS genotype | 35 (85%) | 65 (87%) | 0.85 |
| Baseline total Hb, g/dL | 9.0 [8.0–10.0] | 9.0 [8.0–9.0] | 0.89 |
| Past medical history: | |||
| Previous ACS | 34 (85%) | 62 (83%) | 0.75 |
| Number of previous ACS episodes | 2 [1–3] | 2 [1–3] | 0.84 |
| Previous vaso-occlusive pain crisis | 41 (100%) | 19 (100%) | >0.99 |
| Stroke | 0 (0%) | 2 (3%) | 0.54 |
| Retinopathy | 5 (12%) | 8 (11%) | 0.77 |
| Priapism, % males | 3 (17%) | 7 (23%) | >0.99 |
| Bone necrosis | 10 (24%) | 17 (23%) | 0.83 |
| Heart disease | 8 (20%) | 5 (7%) | 0.06 |
| Treatments | |||
| Chronic transfusions | 5 (13%) | 7 (9%) | 0.75 |
| Chronic hydroxyurea treatment | 18 (45%) | 23 (31%) | 0.13 |
| Long-term home oxygen therapy, % | 2 (5%) | 3 (4%) | >0.99 |
Data are presented as mean±SD, median (25th–75th percentiles] or number (percentage).
ACS, acute chest syndrome.