Mantel summary statistics for all communities, and the core and satellite species groups.
| Mantel test | All | Core | Satellite | ||||
|---|---|---|---|---|---|---|---|
| Parameter A | Parameter B | r | p Value | r | p Value | r | p Value |
| Similarity | FEV1% (pre BD) | −0.167 | <0.0001* | −0.167 | <0.0001* | −0.087 | 0.007 |
| Similarity | FEV1% (post BD) | −0.182 | <0.0001* | −0.182 | <0.0001* | −0.089 | 0.006 |
| Similarity | LCS | −0.126 | <0.00018* | −0.126 | <0.0001* | 0.005 | 0.471 |
| Similarity | Neutrophils | −0.112 | 0.001* | −0.113 | 0.001* | 0.049 | 0.900 |
| Similarity | Gender | −0.072 | 0.028 | −0.072 | 0.027 | −0.047 | 0.108 |
The Mantel statistic r(AB) estimates the correlation (Pearson's correlation coefficient) between two proximity matrices, A and B, and p is used to ascertain whether Mantel regression coefficients were significantly different from 0 following 9999 Monte Carlo permutations. Mantel tests are presented between bacterial community similarity (Bray–Curtis index) and differences in clinical factors.
*p values significant after Bonferroni correction for multiple comparisons (0.05/10=0.005).
BD, bronchodilator; FEV1, forced expiratory volume in 1 s; LCS, Leicester Cough Score.