Shaded cells across the diagonals within each table represent identical results by scorers A and B using the Brody-II scoring system. For air trapping scores >5 and total CT scores >12, only those for which any values were obtained are shown. Although scorer B identified more abnormalities on scans than scorer A as indicated by values generally falling below the shaded diagonal cells (17 (26%) vs 5 (7%) for bronchial dilatation; 27 (42%) vs 17 (26%) for air trapping, the severity of changes were generally very minor, with only seven (11%) and two (3%) of patients having a total CT score ≥12 or 5% of the total possible score). κ=κ coefficient (95% CI) as a measure of agreement of CT subscores and total scores allocated by scorer A and B. It can be seen that the majority of discrepancies for bronchodilatation occurred when changes were deemed to be very minor^(1–3) by one scorer and absent [0] by the other.

LCFC, London Cystic Fibrosis Collaboration; NBS, newborn screened.