Patient demographics and clinical characteristics of the derivation (LTRC) cohort
| Disease group | Control | IPF/UIP | p Value |
|---|---|---|---|
| Number | 50 | 119 | |
| Age—mean (SD) | 47.5 (16.4) | 62.6 (8.7) | 1.50E-12* |
| Gender—% male | 54 | 65 | 0.192† |
| Race—% Caucasian | 82 | 94 | 0.0141† |
| Smoker—N (%) | <0.0001† | ||
| Current | 21 (42) | 0 (0) | |
| Former | 7 (14) | 70 (59) | |
| Never | 20 (40) | 41 (34) | |
| Unknown | 2 (4) | 8 (7) | |
| Pack years—mean (SD)‡ | 22.1 (19.5) | 69.9 (115) | 0.047* |
*By two-tailed t test.
†By χ2 test.
‡Average for current and former smokers.
IPF , idiopathic pulmonary fibrosis; LTRC, Lung Tissue Research Consortium; UIP, usual interstitial pneumonia.