Demographics of incident cases of idiopathic pulmonary fibrosis (IPF) and general population controls
| Characteristic | Cases (n=211) | Controls (n=256) | OR (95% CI)* |
|---|---|---|---|
| Mean age (SD) | 73.7 (8.5) | 70.9 (9.0) | |
| Number of men (%) | 158 (74.9) | 189 (73.8) | |
| Smoking habit (%) | |||
| Never smoked | 59 (28.0) | 113 (44.1) | 1.00 |
| Ex-smokers | 135 (64.0) | 119 (46.5) | 2.32 (1.52 to 3.55) |
| Current smokers | 17 (8.0) | 24 (9.4) | 1.73 (0.83 to 3.62) |
| Previous venous thromboembolic event (%) | 23 (10.9) | 15 (5.9) | 1.65 (0.82 to 3.30) |
| Previous ischaemic heart disease (%) | 66 (31.3) | 43 (16.8) | 1.97 (1.25 to 3.11) |
| Anticoagulant status (%) | |||
| Never been on warfarin | 182 (86.3) | 239 (93.4) | 1.00 |
| Previously been on warfarin | 12 (5.7) | 11 (4.3) | 1.23 (0.92 to 2.94) |
| Currently on warfarin | 17 (8.1) | 6 (2.3) | 2.96 (1.12 to 2.79) |
| Antiplatelet treatment (%) | |||
| Never been on aspirin | 104 (49.3) | 157 (61.3) | 1.00 |
| Previously been on aspirin | 31 (14.7) | 20 (7.8) | 2.05 (1.08 to 3.88) |
| Currently on aspirin | 79 (30.9) | 76 (36.2) | 1.08 (0.71 to 1.66) |
| Highly sensitive C reactive protein category (%) | |||
| <1 mg/mL | 20 (9.5) | 70 (27.3) | 1.00 |
| 1–3 mg/mL | 50 (23.7) | 111 (43.4) | 1.47 (0.79 to 2.75) |
| >3 mg/mL | 137 (64.9) | 63 (24.6) | 8.13 (4.42 to 14.94) |
*All ORs are adjusted for age and sex.