Inflammatory parameters in bronchoalveolar lavage fluid
| Healthy individuals | Allergic asthma patients | |||
|---|---|---|---|---|
| Day −1 | Day 6 | Day −1 | Day 6 | |
| Eosinophils (%) | 0.25 (0.0–2.3) | 0.25 (0.0–4.1) | 1.0 (0.2–9.0) | 1.2 (0.3–9.9) |
| Neutrophils (%) | 2.3 (0.5–8.7) | 1.2* (0.4–3.1) | 0.85 (0.1–4.0) | 1.5 (0.3–9.2) |
| Macrophages (%) | 87.2 (69.9–97.0) | 88.9 (77.9–96.1) | 84.5 (71.0–93.5) | 85.2 (75.3–93.8) |
| Lymphocytes (%) | 6.9 (2.4–28.0) | 8.3 (3.1–21.2) | 10.6 (4.8–23.1) | 10.3 (4.9–17.0) |
| ECP (pg/mL) | 159 (77–698) | 174 (111–459) | 286 (136–3852) | 507* (153–6336) |
| MPO (ng/mL) | 4.16 (0.5–16.45) | 3.85 (0.5–11.93) | 4.04 (0.5–11.83) | 4.16 (0.5–17.87) |
| IL-8 (pg/mL) | 0.9 (0.07–10.55) | 1.25 (0.10–4.04) | 0.34 (0.00–2.33) | 1.42** (0.04–15.75) |
| FeNO (ppb) | 17.5 (7.6–44.0) | 16.5 (9.0–58.0) | 58.7 (24.5–138.6) | 72.2 (28.0–164.1) |
Values are shown as median (range).
Significant differences between healthy individuals and patients with allergic asthma are indicated in Italic.
*p<0.05 (Wilcoxon matched pairs test).
**p=0.098 (Wilcoxon matched pairs test).
ECP, eosinophil cationic protein; FeNO, fractional exhaled nitric oxide; IL, interleukin; MPO, myeloperoxidase; ppb, parts per billion.