Thirty-day clinical events after diagnosis and treatment for haemodynamically stable patients with acute symptomatic PE
| All patients N=848 | Right to left ventricular ratio ≤0.9 on MDCT N=315 | Right to left ventricular ratio >0.9 on MDCT N=533 | p Value | |
|---|---|---|---|---|
| Primary outcome, n (%) | ||||
| All-cause death | 38 (4.5%) | 13 (4.1%) | 25 (4.7%) | 0.702 |
| PE-related death | 11 (1.3%) | 1 (0.3%) | 10 (1.9%) | 0.053 |
| Secondary outcomes, n (%) | ||||
| Recurrent PE | 3 (0.3%) | 1 (0.3%) | 2 (0.4%) | 0.891 |
| Major bleeding | 19 (2.2%) | 5 (1.6%) | 14 (2.6%) | 0.472 |
| Complicated course* | 63 (7.4%) | 20 (6.3%) | 43 (8.1%) | 0.357 |
| Haemodynamic collapse† | 28 (3.3%) | 7 (2.2%) | 21 (3.9%) | 0.174 |
| Non-fatal recurrent PE | 1 (0.1%) | 1 (0.3%) | 0 | – |
*Defined as all-cause mortality, haemodynamic collapse or recurrent PE.
†Defined as the use of at least one of the following: infusion of a catecholamine because of persistent arterial hypotension or shock; endotracheal intubation; cardiopulmonary resuscitation; and rescue thrombolysis, emergency surgical embolectomy or thrombus fragmentation by catheter.
MDCT, multidetector CT; PE, pulmonary embolism.