Cardiac predictors of 30-day complicated course in 848 haemodynamically stable patients with acute symptomatic pulmonary embolism
| Risk factor | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p Value | |
| Age, per year | 1.01 (0.99 to 1.03) | 0.167 | – | – |
| Male gender | 0.82 (0.49 to 1.37) | 0.447 | – | – |
| Cancer | 1.75 (0.96 to 3.18) | 0.067 | – | – |
| Previous VTE | 0.50 (0.19 to 1.26) | 0.141 | – | – |
| Surgery | 0.56 (0.20 to 1.57) | 0.270 | – | – |
| COPD | 1.23 (0.61 to 2.51) | 0.564 | – | – |
| Congestive heart failure | 1.30 (0.49 to 3.39) | 0.597 | – | – |
| Heart rate ≥110/min* | 2.20 (1.27 to 3.80) | 0.005 | – | – |
| SBP<100 mm Hg* | 2.85 (1.13 to 3.80) | 0.026 | – | – |
| RV dysfunction (echocardiogram) | 2.62 (1.54 to 4.45) | <0.001 | – | – |
| Cardiac troponin I>0.05 ng/ml* | 2.84 (1.62 to 4.98) | <0.001 | 1.98 (1.08 to 3.56) | 0.026 |
| Brain natriuretic peptide>100 pg/ml* | 3.21 (1.80 to 5.73) | <0.001 | 2.70 (1.47 to 4.94) | 0.001 |
*Only variables found to significantly predict a 30-day complicated course by univariable analysis were entered in the multivariable model.
COPD, chronic obstructive pulmonary disease; RV, right ventricle; SBP, systolic blood pressure; VTE, venous thromboembolism.