Association of adult onset asthma with ever having worked in ISCO-coded occupation (61 occupations tested, 18 reaching conventional levels of significance)
| Adult onset asthma | Adult onset asthma with airflow limitation† | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Occupation | Case/total | OR | OR* | 95% CI | p Value | q Value | Case/total | OR* | 95% CI | p Value |
| Reference group | 170/2217 | 1.00 | 1.00 | – | – | – | 29/1864 | 1.00 | – | |
| 5122-Cooks | 42/367 | 1.56 | 1.52 | 1.05 to 2.19 | 0.025 | 0.177 | 8/310 | 1.45 | 0.64 to 3.24 | 0.372 |
| 5123-Waiters, waitresses and bartenders | 78/667 | 1.60 | 1.50 | 1.12 to 2.01 | 0.007 | 0.055 | 17/563 | 1.64 | 0.88 to 3.08 | 0.122 |
| 5133-Home-based personal care workers | 60/404 | 2.10 | 1.94 | 1.40 to 2.69 | <0.001 | 0.002 | 11/355 | 1.67 | 0.81 to 3.46 | 0.164 |
| 5141-Hairdressers, barbers, beauticians | 32/218 | 2.07 | 1.88 | 1.24 to 2.85 | 0.003 | 0.027 | 1/176 | – | – | – |
| 5169-Protective services workers | 14/130 | 1.45 | 1.90 | 1.05 to 3.43 | 0.034 | 0.143 | 3/111 | – | – | – |
| 6130-Market-oriented crop and animal producers | 10/57 | 2.56 | 4.26 | 2.06 to 8.80 | <0.001 | 0.002 | 2/48 | – | – | – |
| 7232-Aircraft engine mechanics and fitters | 5/30 | 2.41 | 3.81 | 1.41 to 10.31 | 0.008 | 0.056 | 1/27 | – | – | – |
| 7341-Compositors, typesetters | 10/60 | 2.41 | 3.04 | 1.49 to 6.18 | 0.002 | 0.025 | 3/51 | – | – | – |
| 8263-Sewing machine operators | 19/133 | 2.01 | 1.93 | 1.14 to 3.26 | 0.014 | 0.088 | 4/104 | 1.92 | 0.64 to 5.73 | 0.243 |
| 9130-Cleaners unspecified | 20/156 | 1.77 | 1.58 | 0.95 to 2.63 | 0.078 | 0.234 | 2/125 | – | – | – |
| 9131-Domestic helpers and cleaners | 16/113 | 1.99 | 1.79 | 1.02 to 3.14 | 0.044 | 0.154 | 3/91 | – | – | – |
| 9132-Helpers and cleaners in offices, hotels | 70/516 | 1.89 | 1.82 | 1.34 to 2.48 | <0.001 | 0.002 | 17/431 | 2.25 | 1.19 to 4.24 | 0.012 |
| 9133-Hand-launderers and pressers | 8/50 | 2.29 | 2.26 | 1.03 to 4.98 | 0.043 | 0.154 | – | – | – | – |
| 9151-Messengers, package and luggage porters and deliverers | 12/103 | 1.59 | 2.06 | 1.09 to 3.90 | 0.026 | 0.117 | 2/87 | – | – | – |
| 9152-Doorkeepers, watchpersons | 13/82 | 2.27 | 2.59 | 1.37 to 4.87 | 0.003 | 0.027 | 5/65 | 5.00 | 1.81 to 13.85 | 0.002 |
| 9313-Building construction labourers | 18/208 | 1.14 | 1.92 | 1.12 to 3.27 | 0.017 | 0.097 | 3/176 | – | – | – |
| 9320-Manufacturing labourers | 30/198 | 2.15 | 2.55 | 1.66 to 3.93 | <0.001 | 0.001 | 7/161 | 2.86 | 1.20 to 6.81 | 0.017 |
| 9322-Hand packers and other manufacturing labourers | 22/170 | 1.79 | 1.66 | 1.02 to 2.70 | 0.040 | 0.154 | 9/126 | 4.12 | 1.85 to 9.17 | 0.001 |
Each effect estimate is from a separate model with the reference group being individuals who had always worked in office-based occupations. Note that the groups are not mutually exclusive and are not adjusted for exposure to any of the other agents in the table.
Bold type indicates conventional levels of statistical significance (p<0.05).
The q value corresponds to the minimum false discovery rate at which the test may be called significant (q<0.05).
*Adjusted for sex, smoking, father's social class at birth, region and hay fever.
†Those with asthma but no airflow limitation were coded ‘no’ for this analysis.
ASJEM, Asthma Specific Job Exposure Matrix; ISCO, International Standard Classification of Occupations.