Univariable model | Final model | |||||
RR (95% CI) | p Value | n | RR (95% CI) | p Value | n | |
Current doctor-diagnosed asthma at 6 years | 0.97 (0.91 to 1.04) | 0.36 | 860 | 0.98 (0.92 to 1.04) | 0.56 | 836 |
Current wheeze at 6 years | 0.98 (0.92 to 1.03) | 0.40 | 860 | 0.99 (0.94 to 1.05) | 0.76 | 833 |
Any wheeze at or before 6 years | 1.00 (0.98 to 1.01) | 0.61 | 856 | 1.00 (0.98 to 1.02) | 0.95 | 823 |
Transient wheeze | 1.00 (0.98 to 1.02) | 0.85 | 719 | 1.00 (0.98 to 1.02) | 0.89 | 707 |
Persistent/late wheeze | 0.98 (0.93 to 1.03) | 0.37 | 489 | 0.98 (0.94 to 1.03) | 0.49 | 475 |
Persistent/late wheeze with atopy | 0.90 (0.81 to 0.99) | 0.03 | 257 | 0.91 (0.84 to 0.99) | 0.04 | 251 |
Persistent/late wheeze without atopy | 0.99 (0.91 to 1.06) | 0.73 | 259 | 1.01 (0.94 to 1.09) | 0.73 | 253 |
Data presented as change in RR per 10 nmol/litre change in maternal serum 25-hydroxyvitamin D status at 34 weeks' pregnancy.
Adjusted models: asthma—maternal education, maternal asthma, paternal asthma and paternal rhinitis; wheeze at age 6—maternal education, maternal asthma, paternal rhinitis, pets in the home during the child's infancy; wheeze at or before 6 years—maternal body mass index (BMI), child's gender, maternal education, maternal asthma, paternal asthma, maternal rhinitis; transient wheeze—maternal BMI, child's gender, mother's parity, maternal asthma, maternal rhinitis; persistent/late wheeze—maternal education, smoking during pregnancy, maternal asthma, paternal asthma, maternal rhinitis; persistent/late wheeze with atopy—child's gender, maternal asthma, paternal asthma, paternal rhinitis, pets in the home during infancy; persistent/late wheeze without atopy—maternal age, smoking during pregnancy, maternal asthma, paternal asthma, pets in the home during infancy.