Table 3

Relationship between maternal late-pregnancy 25-hydroxyvitamin D status and offspring asthma and wheeze at age 6 years

	Univariable model			Final model
	RR (95% CI)	p Value	n	RR (95% CI)	p Value	n
Current doctor-diagnosed asthma at 6 years	0.97 (0.91 to 1.04)	0.36	860	0.98 (0.92 to 1.04)	0.56	836
Current wheeze at 6 years	0.98 (0.92 to 1.03)	0.40	860	0.99 (0.94 to 1.05)	0.76	833
Any wheeze at or before 6 years	1.00 (0.98 to 1.01)	0.61	856	1.00 (0.98 to 1.02)	0.95	823
Transient wheeze	1.00 (0.98 to 1.02)	0.85	719	1.00 (0.98 to 1.02)	0.89	707
Persistent/late wheeze	0.98 (0.93 to 1.03)	0.37	489	0.98 (0.94 to 1.03)	0.49	475
Persistent/late wheeze with atopy	0.90 (0.81 to 0.99)	0.03	257	0.91 (0.84 to 0.99)	0.04	251
Persistent/late wheeze without atopy	0.99 (0.91 to 1.06)	0.73	259	1.01 (0.94 to 1.09)	0.73	253

Data presented as change in RR per 10 nmol/litre change in maternal serum 25-hydroxyvitamin D status at 34 weeks' pregnancy.
Adjusted models: asthma—maternal education, maternal asthma, paternal asthma and paternal rhinitis; wheeze at age 6—maternal education, maternal asthma, paternal rhinitis, pets in the home during the child's infancy; wheeze at or before 6 years—maternal body mass index (BMI), child's gender, maternal education, maternal asthma, paternal asthma, maternal rhinitis; transient wheeze—maternal BMI, child's gender, mother's parity, maternal asthma, maternal rhinitis; persistent/late wheeze—maternal education, smoking during pregnancy, maternal asthma, paternal asthma, maternal rhinitis; persistent/late wheeze with atopy—child's gender, maternal asthma, paternal asthma, paternal rhinitis, pets in the home during infancy; persistent/late wheeze without atopy—maternal age, smoking during pregnancy, maternal asthma, paternal asthma, pets in the home during infancy.