Lung function characteristics in patients with COPD and comparator subjects according to sex
| Characteristic | Patients with COPD | Smoker controls | Non-smoker controls | |||
| Men | Women | Men | Women | Men | Women | |
| n | 1207 | 624 | 165 | 120 | 89 | 139 |
| Post-bronchodilator FEV1 change (litres) | 0.13 (0.16) | 0.10 (0.12) | 0.16 (0.18) | 0.11 (0.10) | 0.08 (0.14) | 0.08 (0.13) |
| Pre-bronchodilator % predicted FEV1 | 43.3 (15.0) | 47.4 (14.6) | 102.8 (11.9) | 106.1 (12.1) | 110.6 (13.7) | 113.4 (14.1) |
| Reversible (standard criteria) (% subjects) | 28 | 17 | 6 | 4 | 0 | 4 |
| Maximum FEV1 day-to-day variation (litres) | 0.25 (0.15) | 0.19 (0.11) | 0.28 (0.16) | 0.19 (0.09) | 0.24 (0.15) | 0.18 (0.11) |
| OR (95% CI)* | 1.79 (1.39 to 2.31) | 6.14 (1.56 to 24.22) | ||||
| Post-bronchodilator FEV1 change (% predicted) | 4.3 (5.0) | 4.3 (5.4) | 4.6 (5.6) | 4.2 (4.0) | 2.1 (3.9) | 3.3 (5.5) |
| Reversible (400 ml) (%) | 8 | 2 | 6 | 0 | 0 | 1 |
Data are given as mean (SD) unless otherwise indicated.
↵* The odds of a man classified as reversible versus the odds of a woman classified as reversible after adjusting for FEV1. Note that there is no OR for non-smoker controls because no men were classified as reversible.
COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s.