Diagnostic accuracy of 3% oxygen desaturation index for detection of sleep-disordered breathing in patients with chronic heart failure
| Sensitivity | Specificity | Positive predictive value | Negative predictive value | Positive likelihood ratio | Negative likelihood ratio | Area under ROC curve | |
| All patients with CHF* (n=171) | 97 (91–100) | 32 (22–41) | 53 (45–62) | 94 (79–99) | 1.42 (1.24–1.64) | 0.08 (0.02–0.34) | 0.92 (0.88–0.96) |
| Patients with CHF without %VLFI measurement* (n=94) | 98 (87–100) | 24 (13–35) | 49 (38–60) | 93 (66–100) | 1.28 (1.10–1.50) | 0.10 (0.01–0.76) | 0.92 (0.86–0.98) |
| Patients with CHF with %VLFI measurement* (n=77) | 97 (85–100) | 41 (26–57) | 59 (47–72) | 94 (73–100) | 1.66 (1.28–2.16) | 0.07 (0.01–0.48) | 0.91 (0.85–0.98) |
↵* Diagnostic accuracy values were assessed using the a priori cutoff of >7.5 desaturations/h for diagnosis of sleep-disordered breathing and are presented with 95% CI.
CHF, chronic heart failure; ROC, receiver operating characteristic; %VLFI, % very low frequency increment of heart rate variability.