Table 5

Consistency of reversibility status and clinical outcomes summary of pre-bronchodilator FEV1 at each visit

CharacteristicPatients with COPDGOLD IIGOLD IIIGOLD IVSmoker controlsNon-smoker controls
Pre-bronchodilator FEV1 (visit 1)1.25 (0.49)1.60 (0.44)1.04 (0.28)0.67 (0.15)3.20 (0.72)3.24 (0.79)
Pre-bronchodilator FEV1 (visit 2)1.27 (0.51)1.60 (0.48)1.07 (0.34)0.71 (0.21)3.15 (0.73)3.22 (0.77)
Pre-bronchodilator FEV1 (visit 3)1.26 (0.51)1.58 (0.47)1.06 (0.34)0.71 (0.22)3.15 (0.71)3.21 (0.79)
Pre-bronchodilator FEV1 (visit 4)1.25 (0.50)1.57 (0.47)1.04 (0.33)0.71 (0.23)3.13 (0.71)3.20 (0.78)
Variation between visits277 (195)322 (210)257 (173)179 (150)265 (170)276 (189)
OR for reversibility when below variation on test day2.920 (2.274 to 3.749)2.593 (1.883 to 3.570)3.593 (2.295 to 5.623)5.945 (1.300 to 27.189)2.818 (0.784 to 10.123)>999.999 (<0.001 to >999.999)
  • Data are given as mean (SD) or OR (95% CI).

  • COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; GOLD, Global initiative for chronic Obstructive Lung Disease.