Asthma Quality of Life (AQOL): model-derived estimates for baseline, follow-up and change from baseline
| Mean (SE) | Mean change (95% CI) from baseline to: | ||||||
| Baseline | 10 weeks | 6 months | 12 months | 10 weeks | 6 months | 12 months | |
| AQOL overall score | n=82 | n=74 | n=76 | n=80 | |||
| MBSR | 5.10 (0.17) | 5.61 (0.17) | 5.70 (0.17) | 5.82 (0.17) | 0.51 (0.25 to 0.77) | 0.60 (0.37 to 0.84) | 0.72 (0.46 to 0.99) |
| HLC control | 5.33 (0.17) | 5.57 (0.17) | 5.61 (0.17) | 5.39 (0.16) | 0.24 (−0.02 to 0.51) | 0.28 (0.05 to 0.52) | 0.06 (−0.20 to 0.32) |
| Differential change | 0.27 (−0.11 to 0.64) | 0.32 (−0.01 to 0.65) | 0.66 (0.30 to 1.03) | ||||
| p Value | 0.162 | 0.054 | <0.001 | ||||
| Four AQOL domains | |||||||
| Activity limitations | n=82 | n=74 | n=76 | n=80 | |||
| MBSR | 4.99 (0.18) | 5.42 (0.17) | 5.63 (0.18) | 5.77 (0.18) | 0.43 (0.14 to 0.72) | 0.64 (0.33 to 0.95) | 0.78 (0.47 to 1.09) |
| HLC control | 5.25 (0.18) | 5.56 (0.17) | 5.62 (0.19) | 5.37 (0.18) | 0.31 (0.02 to 0.60) | 0.37 (0.06 to 0.68) | 0.12 (−0.19 to 0.42) |
| Differential change | 0.13 (−0.28 to 0.54) | 0.27 (−0.17 to 0.71) | 0.66 (0.22 to 1.10) | ||||
| p Value | 0.547 | 0.270 | 0.003 | ||||
| Symptoms | n=82 | n=73 | n=76 | n=80 | |||
| MBSR | 5.10 (0.18) | 5.66 (0.19) | 5.71 (0.18) | 5.80 (0.18) | 0.56 (0.24 to 0.88) | 0.61 (0.36 to 0.86) | 0.70 (0.41 to 1.00) |
| HLC control | 5.28 (0.18) | 5.53 (0.19) | 5.55 (0.18) | 5.35 (0.18) | 0.26 (−0.07 to 0.58) | 0.28 (0.02 to 0.53) | 0.07 (−0.22 to 0.36) |
| Differential change | 0.31 (−0.14 to 0.76) | 0.33 (−0.02 to 0.69) | 0.63 (0.22 to 1.04) | ||||
| P Value | 0.181 | 0.065 | 0.002 | ||||
| Emotional function | n=82 | n=74 | n=76 | n=80 | |||
| MBSR | 5.20 (0.21) | 5.81 (0.21) | 5.94 (0.16) | 6.14 (0.17) | 0.61 (0.27 to 0.95) | 0.74 (0.44 to 1.05) | 0.94 (0.58 to 1.30) |
| HLC control | 5.37 (0.21) | 5.67 (0.21) | 5.70 (0.17) | 5.50 (0.17) | 0.29 (−0.05 to 0.64) | 0.33 (0.02 to 0.64) | 0.13 (−0.23 to 0.49) |
| Differential change | 0.32 (−0.16 to 0.81) | 0.42 (−0.02 to 0.85) | 0.81 (0.30 to 1.33) | ||||
| p Value | 0.194 | 0.060 | 0.002 | ||||
| Environmental stimuli | n=80 | n=73 | n=76 | n=79 | |||
| MBSR | 5.29 (0.19) | 5.69 (0.21) | 5.63 (0.19) | 5.64 (0.21) | 0.40 (0.07 to 0.72) | 0.34 (0.05 to 0.62) | 0.35 (0.03 to 0.68) |
| HLC control | 5.57 (0.19) | 5.64 (0.21) | 5.67 (0.19) | 5.41 (0.21) | 0.07 (−0.26 to 0.40) | 0.10 (−0.20 to 0.39) | −0.16 (−0.48 to 0.17) |
| Differential change | 0.33 (−0.13 to 0.79) | 0.24 (−0.18 to 0.65) | 0.51 (0.05 to 0.97) | ||||
| p Value | 0.161 | 0.258 | 0.028 | ||||
Differential change was calculated as the difference in change from baseline for the intervention versus change from baseline for the comparison group. The differing numbers of individuals included in each outcome analysis is due to the AQOL allowing for differing numbers of missing responses for each subscale.
HLC, healthy living course; MBSR, mindfulness-based stress reduction.