Lung function: model estimates for baseline, follow-up and change from baseline
| Mean (SE) | Mean change (95% CI) from baseline to: | ||||||
| Baseline | 10 weeks | 6 months | 12 months | 10 weeks | 6 months | 12 months | |
| 2-Week average morning PEF (litres/min) | n=80 | n=81 | n=82 | n=82 | |||
| MBSR | 445.1 (21.5) | 444.7 (22.2) | 444.5 (21.4) | 440.9 (22.3) | −0.3 (−22.5 to 21.8) | −0.6 (−23.7 to 22.5) | −4.2 (−31.2 to 22.8) |
| HLC control | 393.4 (22.0) | 401.8 (22.7) | 402.2 (21.9) | 400.0 (22.8) | 8.4 (−14.4 to 31.1) | 8.8 (−14.9 to 32.5) | 6.5 (−21.1 to 34.2) |
| Differential change | −8.7 (−40.4 to 23.0) | −9.4 (−42.5 to 23.7) | −10.7 (−49.3 to 28.0) | ||||
| p Value | 0.591 | 0.578 | 0.588 | ||||
| PEF variability (%) | n=77 | n=80 | n=82 | n=82 | |||
| MBSR | 8.86 (0.78) | 7.86 (0.71) | 8.91 (0.70) | 8.59 (0.97) | −1.00 (−2.22 to 0.23) | 0.06 (−1.51 to 1.62) | −0.27 (−2.26 to 1.72) |
| HLC control | 9.12 (0.79) | 8.50 (0.72) | 7.51 (0.72) | 9.07 (0.99) | −0.62 (−1.86 to 0.62) | −1.61 (−3.19 to −0.03) | −0.05 (−2.07 to 1.97) |
| Differential change | −0.38 (−2.12 to 1.36) | 1.67 (−0.56 to 3.89) | −0.22 (−3.05 to 2.62) | ||||
| p Value | 0.672 | 0.142 | 0.879 | ||||
| Spirometry (FEV1) (litres) | n=83 | n=83 | n=83 | n=83 | |||
| MBSR | 2.57 (0.10) | 2.60 (0.10) | 2.61 (0.11) | 2.60 (0.11) | 0.03 (−0.03 to 0.09) | 0.05 (−0.02 to 0.11) | 0.04 (−0.05 to 0.12) |
| HLC control | 2.54 (0.10) | 2.63 (0.11) | 2.60 (0.11) | 2.56 (0.11) | 0.09 (0.03 to 0.15) | 0.06 (−0.01 to 0.13) | 0.02 (−0.06 to 0.10) |
| Differential change | −0.06 (−0.14 to 0.03) | −0.01 (−0.11 to 0.08) | 0.01 (−0.10 to 0.13) | ||||
| p Value | 0.213 | 0.761 | 0.809 | ||||
Differential change was calculated as the difference in change from baseline for the intervention versus change from baseline for the comparison group. The differing numbers of individuals included in each outcome analysis is due to missing data, as not all patients completed these measurements at all time points.
FEV1, forced expiratory volume in 1 s; HLC, healthy living course; MBSR, mindfulness-based stress reduction; PEF, peak expiratory flow.