Results of LiPA compared with culture in detecting Mycobacterium tuberculosis complex (2003–2009)
| Sample and AFB smear results (2003–2009) | Sensitivity (%) | CI | Specificity (%) | CI | PPV (%) | CI | NPV (%) | CI | Accuracy (%) | CI |
| All* † | 2876\3296 (87.3) | 86.1 to 88.4 | 4137\4540 (91.1) | 90.2 to 91.9 | 2876\3279 (87.7) | 86.5 to 88.8 | 4137\4557 (90.8) | 89.9 to 91.6 | 7013\7836 (89.5) | 88.8 to 90.2 |
| All smear +ve | 2421\2604 (93.0) | 91.9 to 93.9 | 782\1032 (75.8) | 73.0 to 78.3 | 2421\2671 (90.6) | 89.5 to 91.7 | 782\965 (81.0) | 78.4 to 83.4 | 3203\3636 (88.1) | 87.0 to 89.1 |
| All smear −ve | 260\438 (59.4) | 54.6 to 64.0 | 2522\2638 (95.6) | 94.7 to 96.3 | 260\376 (69.1) | 64.2 to 73.7 | 2522\2700 (93.4) | 92.4 to 94.3 | 2782\3076 (90.4) | 89.3 to 91.4 |
| Respiratory* | 2375\2595 (91.5) | 90.4 to 92.6 | 1628\1825 (89.2) | 87.4 to 90.3 | 2375\2572 (92.3) | 91.0 to 93.2 | 1628\1848 (88.1) | 86.5 to 89.5 | 4003\4420 (90.6) | 89.6 to 91.3 |
| Respiratory smear +ve | 2083\2221 (93.8) | 92.7 to 94.7 | 644\782 (82.4) | 79.5 to 84.9 | 2083\2221 (93.8) | 92.7 to 94.7 | 644\782 (82.4) | 79.5 to 84.9 | 2727\3003 (90.8) | 89.7 to 91.8 |
| Respiratory smear −ve | 145\206 (70.4) | 63.6 to 76.4 | 829\867 (95.6) | 94.0 to 96.8 | 145\183 (79.2) | 72.5 to 84.7 | 829\890 (93.1) | 91.2 to 94.7 | 974\1073 (90.8) | 88.8 to 92.4 |
| Non-respiratory* | 500\700 (71.4) | 68.3 to 74.9 | 2500\2706 (92.4) | 91.6 to 93.6 | 500\706 (70.8) | 68.4 to 75.0 | 2500\2700 (92.6) | 91.6 to 93.5 | 3000\3406 (88.1) | 87.2 to 89.3 |
| Non-respiratory smear +ve | 328\373 (87.9) | 84.5 to 91.2 | 137\246 (55.7) | 49.0 to 61.8 | 328\437 (75.1) | 71.2 to 79.4 | 137\182 (75.3) | 68.1 to 81.1 | 465\619 (75.1) | 71.8 to 78.7 |
| Non- respiratory smear −ve | 114\231 (49.4) | 42.7 to 55.7 | 1690\1768 (95.6) | 94.6 to 96.5 | 114\192 (59.4) | 52.7 to 66.7 | 1690\1807 (93.5) | 92.3 to 94.5 | 1804\1999 (90.2) | 88.9 to 91.5 |
| Sputum* | 2089\2237 (93.4) | 92.3 to 94.4 | 980\1145 (85.6) | 83.4 to 87.5 | 2089\2254 (92.7) | 91.5 to 93.7 | 980\1128 (86.9) | 84.7 to 88.8 | 3069\3382 (90.7) | 89.7 to 91.7 |
| Sputum smear +ve | 1862\1966 (94.7) | 93.6 to 95.6 | 518\640 (80.9) | 77.6 to 83.9 | 1862\1984 (93.9) | 92.7 to 94.8 | 518\622 (83.3) | 80.1 to 86.1 | 2380\2606 (91.3) | 90.2 to 92.4 |
| Sputum smear −ve | 98\126 (77.8) | 69.3 to 84.5 | 368\397 (92.7) | 89.6 to 95.0 | 98\127 (77.2) | 68.7 to 83.9 | 368\396 (92.9) | 89.8 to 95.2 | 466\523 (89.1) | 86.0 to 91.6 |