Association between lung cancer risk and exposure to organic dust, stratified by histology
| Exposure to organic dust | Controls | Squamous and small cell carcinoma | Adenocarcinoma | ||
| n | n | OR* (95% CI) | N | OR* (95% CI) | |
| Total population | |||||
| Never | 8940 | 3520 | 1.00 (reference) | 1816 | 1.00 (reference) |
| First quartile | 1770 | 868 | 1.10 (0.99 to 1.22) | 382 | 0.92 (0.81 to 1.05) |
| Second quartile | 1914 | 1115 | 1.25 (1.13 to 1.38) | 455 | 1.00 (0.88 to 1.13) |
| Third quartile | 1804 | 996 | 1.23 (1.11 to 1.36) | 392 | 1.01 (0.88 to 1.15) |
| Fourth quartile | 1845 | 1146 | 1.39 (1.26 to 1.54) | 347 | 0.97 (0.84 to 1.11) |
| Test for trend, p value† | <0.001 | 0.950 | |||
| Never smokers | |||||
| Never | 2971 | 144 | 1.00 (ref) | 251 | 1.00 (ref) |
| First quartile | 498 | 36 | 1.17 (0.78 to 1.76) | 44 | 0.76 (0.54 to 1.09) |
| Second quartile | 576 | 41 | 1.18 (0.80 to 1.75) | 54 | 0.84 (0.60 to 1.16) |
| Third quartile | 540 | 47 | 1.50 (1.04 to 2.16) | 57 | 0.95 (0.69 to 1.31) |
| Fourth quartile | 592 | 44 | 1.16 (0.78 to 1.75) | 51 | 0.87 (0.61 to 1.21) |
| Test for trend, p value† | 0.106 | 0.819 | |||
* ORs are adjusted for age, sex, study, pack-years, time since quitting smoking (if appropriate), and ever employment in a ‘list A job’.
† p Values for trend result from a logistic regression model with exposure as a continuous variable.