Table 2

ORs for associations between venous thromboemboli (VTE) and haemorrhage-associated variables

NAge-adjusted ORN'Age and fibrinogen-adjusted OR
All VTE
 Serum iron, at VTE4930.91 (0.86 to 0.97)4490.90 (0.84 to 0.97)
 Serum TfSI, at VTE4940.95 (0.92 to 0.99)4500.95 (0.91 to 0.99)
 Ferritin2431.00 (0.98 to 1.01)2260.99 (0.98 to 1.01)
 Haemoglobin5430.94 (0.81 to 1.05)4870.94 (0.80 to 1.11)
 Platelets5501.00 (1.00 to 1.01)4951.00 (1.00 to 1.01)
 On iron treatment (oral)5931.52 (0.73 to 3.20)4961.93 (0.89 to 4.20)
 Ever transfused5990.93 (0.31 to 2.84)4941.00 (0.32 to 3.14)
 Using hormones5910.92 (0.31 to 2.70)4871.11 (0.37 to 3.34)
 Using tranexamic acid5921.02 (1.00 to 1.05)4891.30 (0.27 to 6.05)
Community restricted
 Serum iron, at VTE4930.91 (0.84 to 0.99)4490.90 (0.82 to 0.99)
 Serum TfSI, at VTE4940.95 (0.91 to 0.996)4500.94 (0.89 to 0.99)
 Ferritin2431.00 (0.98 to 1.01)2261.00 (0.98 to 1.01)
 Haemoglobin5430.89 (0.72 to 1.09)4870.89 (0.72 to 1.10)
 Platelets5501.00 (1.00 to 1.01)4951.00 (0.99 to 1.01)
 On iron treatment (oral)5990.90 (0.32 to 2.490)4961.07 (0.37 to 3.10)
 Ever transfused5990.94 (0.20 to 4.35)4941.00 (0.21 to 4.74)
 Using hormones5911.80 (0.58 to 5.54)4871.55 (0.43 to 5.64)
 Using tranexamic acid5930.94 (0.12 to 7.40)4891.25 (0.15 to 10.23)
  • ORs for all VTE occurring in series 1 and 2 combined, with ORs significantly different to 1.00 denoted in bold. A series indicator variable was used to confirm the validity of series pooling. N, number of observations for age-adjusted figures; N', number including fibrinogen, selected as acute phase markers because available in 449 patients compared with 320 for C-reactive protein. Intravenous iron could not be part of any model due to the low frequency of use. TfSI, transferrin saturation index.