Initial antimicrobial treatment and outcomes
| Variable | Patients with CAP≥65 years (n=2569) | Patients with NHAP≥65 years (n=518) | p Value |
| Prior antibiotic therapy*, n (%) | 481 (18.9) | 73 (14.5) | 0.019 |
| Initial antibiotic therapy, n (%) | 2550 (99.3) | 513 (99.0) | 0.523 |
| Monotherapy, n (%) | 1476 (57.9) | 396 (77.2) | <0.001 |
| Combination, n (%) | 1067 (41.8) | 117 (22.8) | <0.001 |
| Duration of antibiotic therapy, days (median (IQR) (n)) | 10 (6) (2342) | 10 (6) (400) | <0.001 |
| Change in antibiotic therapy, n (%) | 876 (36.6) | 176 (42.4) | 0.023 |
| ß-Lactam antibiotics, n (%) | 2216 (86.9) | 470 (91.6) | 0.003 |
| Penicillins, n (%) | 1258 (49.3) | 280 (54.6) | 0.030 |
| Cephalosporins, n (%) | 941 (36.9) | 193 (37.6) | 0.758 |
| Carbapenems, n (%) | 29 (1.1) | 5 (1.0) | 0.748 |
| Macrolides, n (%) | 980 (38.4) | 85 (16.6) | <0.001 |
| Quinolones, n (%) | 358 (14.0) | 54 (10.5) | 0.033 |
| Tetracylines, n (%) | 9 (0.4) | 0 (0.0) | 0.178 |
| Glycopeptides, n (%) | 6 (0.2) | 0 (0.0) | 0.271 |
| Lincosamides, n (%) | 15 (0.6) | 4 (0.8) | 0.614 |
| Ketolides, n (%) | 1 (0.0) | 0 (0.0) | 0.654 |
| co-Trimoxazole, n (%) | 6 (0.2) | 2 (0.4) | 0.531 |
| Aminoglycosides, n (%) | 8 (0.3) | 4 (0.8) | 0.123 |
| Other antibiotics, n (%) | 11 (0.4) | 10 (1.9) | <0.001 |
| Died within 30 days, n (%) | 172 (7.2) | 105 (26.6) | <0.001 |
| Died within 180 days, n (%) | 352 (14.6) | 173 (43.8) | <0.001 |
↵* Antibiotic therapy during the last 4 weeks.
CAP, community-acquired pneumonia; NHAP, nursing-home-acquired pneumonia.