Results of Cox regression analyses using all patient features, all NHS trust level features, surgical intervention or not and clustering by NHS trust (n=34 365)
| No of patients | No who died | (%)* | Unadjusted HR (95% CI) | Adjusted HR† (95% CI) | p Value | |
| Sex | ||||||
| Male | 20 848 | 17 144 | 82 | |||
| Female | 13 517 | 10 616 | 79 | 0.90 (0.88 to 0.92) | 0.90 (0.88 to 0.92) | <0.001 |
| Age quintile | ||||||
| 1 (30–62 years) | 8183 | 6372 | 78 | <0.001‡ | ||
| 2 (63–69 years) | 7616 | 5897 | 77 | 1.02 (0.98 to 1.06) | 1.04 (1.00 to 1.07) | |
| 3 (70–75 years) | 7660 | 6210 | 81 | 1.15 (1.11 to 1.19) | 1.10 (1.06 to 1.14) | |
| 4 (76–80 years) | 6084 | 5068 | 83 | 1.28 (1.24 to 1.33) | 1.17 (1.13 to 1.22) | |
| 5 (81–100 years) | 4822 | 4213 | 87 | 1.57 (1.51 to 1.64) | 1.32 (1.26 to 1.39) | |
| Stage | ||||||
| IA | 1177 | 448 | 38 | <0.001‡ | ||
| IB | 2137 | 1062 | 50 | 1.43 (1.28 to 1.60) | 1.27 (1.11 to 1.46) | |
| IIA | 202 | 79 | 39 | 1.03 (0.81 to 1.31) | 1.00 (0.79 to 1.28) | |
| IIB | 1446 | 905 | 63 | 2.08 (1.85 to 2.32) | 1.71 (1.48 to 1.99) | |
| IIIA | 2772 | 2083 | 75 | 2.82 (2.55 to 3.13) | 1.98 (1.73 to 2.27) | |
| IIIB | 5410 | 4564 | 84 | 4.09 (3.71 to 4.50) | 2.67 (2.33 to 3.05) | |
| IV | 10 913 | 10 106 | 93 | 6.37 (5.80 to 7.01) | 3.85 (3.35 to 4.42) | |
| Occult | 50 | 26 | 52 | 1.56 (1.05 to 2.31) | 1.24 (0.83 to 1.86) | |
| Missing | 10 258 | 8487 | 83 | 3.93 (3.57 to 4.32) | 2.53 (2.19 to 2.91) | |
| Performance status | ||||||
| 0 | 5839 | 3804 | 65 | <0.001‡ | ||
| 1 | 9267 | 7226 | 78 | 1.49 (1.43 to 1.55) | 1.28 (1.22 to 1.33) | |
| 2 | 5300 | 4737 | 89 | 2.50 (2.40 to 2.61) | 1.87 (1.76 to 1.99) | |
| 3 | 3230 | 3103 | 96 | 4.51 (4.30 to 4.74) | 3.12 (2.91 to 3.35) | |
| 4 | 737 | 722 | 98 | 7.62 (7.03 to 8.25) | 5.21 (4.39 to 6.17) | |
| Missing | 9992 | 8168 | 82 | 1.82 (1.75 to 1.89) | 1.54 (1.45 to 1.62) | |
| Ethnic group | ||||||
| White | 26 408 | 21 488 | 81 | 0.0004§ | ||
| Black | 231 | 177 | 77 | 0.84 (0.72 to 0.97) | 0.81 (0.70 to 0.93) | |
| Asian | 1897 | 1433 | 76 | 0.98 (0.93 to 1.03) | 0.95 (0.89 to 1.02) | |
| Mixed race | 103 | 84 | 82 | 0.86 (0.77 to 1.18) | 0.96 (0.79 to 1.18) | |
| Other | 160 | 115 | 72 | 0.83 (0.69 to 1.00) | 0.86 (0.73 to 1.02) | |
| Missing | 5566 | 4463 | 80 | 1.03 (1.00 to 1.06) | 1.05 (1.01 to 1.09) | |
| Townsend quintile | ||||||
| 1 (most affluent) | 5172 | 4161 | 80 | 0.661‡ | ||
| 2 | 6363 | 5128 | 81 | 1.01 (0.97 to 1.05) | 1.00 (0.96 to 1.05) | |
| 3 | 6627 | 5345 | 81 | 1.03 (0.99 to 1.06) | 1.00 (0.96 to 1.05) | |
| 4 | 7115 | 5671 | 80 | 1.01 (0.97 to 1.05) | 0.99 (0.94 to 1.03) | |
| 5 (least affluent) | 9011 | 7390 | 82 | 1.04 (1.00 to 1.08) | 0.99 (0.94 to 1.05) | |
| Missing | 77 | 65 | 84 | 1.12 (0.87 to 1.42) | 0.87 (0.67 to 1.14) | |
| Charlson index | ||||||
| 0 | 15 536 | 12 105 | 78 | <0.001‡ | ||
| 1 | 6931 | 5431 | 78 | 1.10 (1.06 to 1.13) | 1.06 (1.02 to 1.09) | |
| 2 or 3 | 5795 | 4592 | 79 | 1.16 (1.12 to 1.20) | 1.07 (1.03 to 1.11) | |
| 4+ | 6103 | 5632 | 92 | 2.00 (1.93 to 2.06) | 1.59 (1.52 to 1.66) | |
| Surgery | ||||||
| No | 29 887 | 25 940 | 87 | |||
| Yes | 4478 | 1820 | 41 | 0.24 (0.23 to 0.25) | 0.41 (0.39 to 0.44) | <0.001 |
| Surgery centre | ||||||
| No | 25 131 | 20 517 | 82 | |||
| Yes | 9234 | 7243 | 79 | 0.91 (0.89 to 0.94) | 0.95 (0.89 to 1.01) | 0.09 |
| Radiotherapy centre | ||||||
| No | 21 536 | 17 550 | 81 | |||
| Yes | 12 829 | 10 210 | 80 | 0.97 (0.95 to 0.99) | 1.02 (0.96 to 1.09) | 0.539 |
| Trial centre | ||||||
| Poor | 23 043 | 18 642 | 81 | |||
| Good | 11 322 | 9118 | 81 | 0.98 (0.95 to 1.00) | 1.01 (0.96 to 1.06) | 0.734 |