Patient investigations and treatment
| SUVmax (g/ml) | Operation | Histology | Aspergillus IgG (mg/l) | Precipitin titre | Total IgE (kIU/l) | Aspergillus IgE (kUa/l) | Diagnosis | Treatment | |
| Case 1 | 7.2 | Wedge resection | Septate fungal hyphae and conidial heads | 78 | 1/2 | 42 | 0.5 | CPA | Itraconazole |
| Case 2 | 8.3 | Wedge resection | Hyphal fragments | >200 | 1/2 | 8045 | 36.7 | ABPA | Itraconazole |
| Case 3 | 4.0 | Wedge resection | Fungal hyphae involving adjacent blood vessels | 28 | 1/2 | 1100 | 40.5 | Subacute IA | Voriconazole |
| Case 4 | 3.5 | CT-guided biopsy | Fungal hyphae admixed with spores | 82 | 1/2 | 90 | <0.4 | CPA | Posaconazole |
| Case 5 | 2.6 | Wedge resection | Branching fungal hyphae | 66 | 1/16 | 570 | 8.0 | CPA | Itraconazole |
| Case 6 | 3.9 | CT-guided biopsy | Branching fungal hyphae | 94 | 1/4 | 140 | <0.4 | CPA | Itraconazole |
| Case 7 | 2.2 | Wedge resection | Fungal hyphae admixed with spores | 56 | Neat | 1000 | 14.9 | CPA | Itraconazole |
| Case 8 | 7.9 | Wedge resection | Branching fungal hyphae | 50 | Neat | 73 | <0.4 | CPA | Voriconazole |
| Case 9 | 9.0 | CT-guided biopsy | Branching fungal hyphae | 76 | 1/64 | 62 | <0.4 | CPA | Itraconazole |
| Case 10 | 2.9 | Lobectomy | Aspergilloma | – | 1/2 | 61 | <0.4 | Simple aspergilloma | No antifungals |
IgE and IgG determinations were performed by ImmunoCAP assay (Phadia) and precipitins by immunoelectrophoresis (using antigens from Microgen Bioproducts, Surrey, UK).
ABPA, allergic bronchopulmonary aspergillosis; CPA, chronic pulmonary aspergillosis; IA, invasive aspergillosis, Ig, immunoglobulin; SUVmax, maximum standardised uptake value.