Inert gas rebreathing measurements during submaximal constant-load exercise in 6MWD subgroups
| High 6MWD group (n=12) | Low 6MWD group (n=12) | |||||
| Baseline | Follow-up | p Value | Baseline | Follow-up | p Value | |
| 6MWD, metres | 477±80 | 477±97 | 0.991 | 291±47 | 325±61 | <0.001 |
| PBF, l/min | ||||||
| Supine rest | 4.1±0.9 | 5.0±1.4 | 0.013 | 3.8±1.2 | 4.3±1.3 | 0.068 |
| Erect rest | 3.3±0.5 | 4.1±1.0 | 0.012 | 3.1±0.7 | 3.8±0.8 | 0.004 |
| Exercise | 5.6±1.8 | 6.5±2.1 | 0.031 | 5.0±1.7 | 5.6±1.9 | 0.030 |
| SV, ml | ||||||
| Supine rest | 55 (38–73) | 64±18 | 0.084 | 47 (29–62) | 57 (37–62) | 0.010 |
| Erect rest | 43±10 | 52±14 | 0.027 | 37 (24–42) | 48±16 | 0.001 |
| Exercise | 52±17 | 62±21 | 0.030 | 44±19 | 49±19 | 0.064 |
Data are expressed as mean±SD or median (IQR).
6MWD, 6-min walk distance; PBF, pulmonary blood flow; SV, stroke volume.