Parameter | Healthy | Asthmatics | Units | p Value |
BW total cells | 9.2 (5.7–10.0) | 8.2 (6.6–10.8) | Cells/ml×104 | NS |
BW neutrophil | 0.85 (0.44–1.52) | 0.85 (0.43–1.17) | Cells/ml×104 | NS |
SM neutrophil | 62 (31–78) | 82 (32–108) | Cells/mm2 | NS |
BW lymphocyte | 0.23 (0.08–0.33) | 0.14 (0.06–0.35) | Cells/ml×104 | NS |
SM CD3+ | 42 (24–58) | 34 (17–77) | Cells/mm2 | NS |
BW eosinophil | 0.01 (0–0.04) | 0.05 (0.01–0.12) | Cells/ml×104 | 0.013 |
SM eosinophil | 0.000 (0–0) | 0.00 (0–0.61) | Cells/mm2 | 0.021 |
BW mast cell | 0.000 (0–0.003) | 0.005 (0.002–0.016) | Cells/ml×104 | <0.001 |
SM mast cell | 19 (11–27) | 22 (13–28) | Cells/mm2 | NS |
BW IL-6 | 3.2 (1.6–4.9) | 3.1 (2.1–4.6) | pg/ml | NS |
BW IL-8 | 47 (20–95) | 32 (22–81) | pg/ml | NS |
BW MPO | 4.9 (3.1–9.4) | 6.5 (4.0–13.8) | μg/l | NS |
BW SCF | 16.8 (13.8–19.5) | 15.2 (13.4–17.5) | pg/ml | NS |
ICAM-1 | 69 (57–89) | 69 (52–93) | % of total EN4 staining | NS |
VCAM-1 | 5.6 (2.5–9.8) | 2.6 (0.6–5.9) | % of total EN4 staining | 0.023 |
Data are presented as median and IQR.
BW, bronchial wash; CD3+, T lymphocytes; ICAM, intracellular adhesion molecule; IL, interleukin; MPO, myeloperoxidase; NS, non-significant; SCF, stem cell factor; SM, bronchial biopsy submucosa; VCAM, vascular cell adhesion molecule.