Subject no. | Duration of exposure (years) | Duration of symptoms (years) | Atopic status (years)* | Specific prick tests | FEV1 (% pred) | PC20 (mg/ml) | Specific reactions |
1 | 1.4 | 1 | + | +Lactoserum (10 mg/ml)+Casein (1 mg/ml) | 87 | 1.3 | Immediate (10 min; 28%) lactoserum |
Late (240 min; 33%) casein† | |||||||
2 | 26 | 2.5 | + | ND lactoserum+Wheat flour | 77 | 0.8 | Immediate (10 min; 29%) lactoserum |
Immediate (10 min; 23%) wheat flour | |||||||
3 | 6 | 1 | + | +Camomile (10 mg/ml)+Ginger (10 mg/ml) | 85 | 7 | Immediate (10 min; 24%) camomile‡ |
Immediate (20 min; 32%) ginger | |||||||
4 | 10 | 7 | + | +Guar gum (10 mg/ml)+Wheat flour | 118 | 4 | Immediate (20 min; 23%) guar gum |
Immediate (10 min; 20%) wheat flour | |||||||
5 | 11 | 1 | + | −Lactoserum (10 mg/ml)+Wheat flour | 84 | 1.6 | Immediate (10 min; 20%) lactoserum |
Immediate (10 min; 22%) wheat flour |
↵* Atopic status: + if one or more positive prick test reactions to a battery of 15 common aeroallergens; the wheat flour extract used was a commercial preparation at a dilution of 1:10 (Omega, Montreal, Canada).
↵† Immediate fall in FEV1 of 13% followed by the late reaction.
↵‡ Immediate reaction followed by a late fall in FEV1 of 16%.
FEV1, forced expiratory volume in one second; ND, not done; PC20, concentration of methacholine causing a fall of 20% in FEV1.