Table 4

Comparison of parameters between iron-deficient and iron-replete patients with IPAH

CharacteristicsIron-deficientIron-repletep Value
Number of patients2659
Age, years45.5 (15.4)55.2 (16.1)0.02
RAP, mm Hg9.5 (5.0)9.5 (5.6)0.95
Mean PA pressure, mm Hg55.9 (11.2)50.3 (14.0)0.06
CI, l/m22.1 (0.6)1.9 (0.6)0.39
Pulmonary vascular resistance, dynes.cm−5939 (408)1000 (486)0.55
6MWD, m320 (122)320 (115)0.97
Proportion ANA-positive3/26 (11.5%)11/59 (18.6%)0.54
Proportion with saturation <95% on room air12/26 (46.2%)23/59 (40.0%)0.79
Proportion treated with ERAs13/26 (50.0%)17/59 (28.8%)0.09
  • ANA, antinuclear antibody; CI, cardiac index; ERA, endothelin receptor antagonist; IPAH, idiopathic pulmonary arterial hypertension; 6MWD, 6-minute walking distance; PA, pulmonary artery; RAP, right atrial pressure.