Asthma treatment | Asthma severity | ||||||
Control | No treatment | Inhaled corticosteroids | p Value | Mild | Moderate–severe | p Value | |
n | 51 | 52 | 71 | 58 | 65 | ||
Age | 29.8 (27.4 to 30.9)* | 25.7 (23 to 27) | 26.7 (25 to 28) | <0.001 | 26.0 (23.4 to 26.8) | 26.5 (25.0 to 28.0) | <0.001 |
Height (cm) | 164.2 (162.2 to 165.9) | 164.1 (161.8 to 166.1) | 164.0 (162.7 to 165.8) | 0.99 | 163.4 (162.0 to 166.0) | 164.4 (162.6 to 165.8) | 0.81 |
Weight (early) (kg) | 73.9 (65.0 to 77.4) | 76.9 (69.2 to 81.1 | 75.3 (69.8 to 81.3) | 0.80 | 77.4 (68.9 to 80.7) | 74.7 (70.0 to 81.6) | 0.67 |
Weight (late) (kg) | 83.0 (76.6 to 87.9) | 88.3 (81.7 to 92.9 | 85.4 (80.5 to 91.2) | 0.47 | 88.1 (82.2 to 92.8) | 85.3 (80.2 to 91.2) | 0.47 |
BMI | 27.4 (24 to 29) | 28.3 (26 to 30) | 27.7 (26 to 30) | 0.82 | 28.3 (25 to 30) | 27.7 (26 to 30) | 0.82 |
Gravida (median, range) | 2 (1–10) | 2 (1–8) | 2 (1–8) | 0.11 | 2 (1–8) | 2 (1–8) | 0.020 |
Parity (median, range) | 1 (0–6)* | 0 (0–4) | 1 (0–6) | 0.011 | 0 (0–4) | 1 (0–6) | 0.004 |
FEV1 | 3.2 (3.0 to 3.4) | 3.2 (3.0 to 3.3) | 3.0 (2.9 to 3.2) | 0.10 | 3.2 (3.0 to 3.4) | 3.0 (2.8 to 3.2)† | 0.043 |
Vital capacity | 3.9 (3.8 to 4.1) | 3.8 (3.6 to 4.0) | 3.8 (3.6 to 3.9) | 0.70 | 3.8 (3.6 to 3.9) | 3.8 (3.6 to 3.9) | 0.71 |
GC dose, third trimester | 0 | 0 | 1054.2 (890.7 to 1233.2)‡ | <0.001 | 234.5 (123.8 to 350.3)§ | 928.0 (705.9 to 1117.5)‡ | <0.001 |
Smoking n (%) | 3 (5.9%) | 14 (26.9%) | 20 (28.2%) | 0.006 | 12 (20.7%)§ | 22 (33.8%)§ | 0.001 |
Significance values represent a comparison of each asthma treatment and the control group and of each asthma severity and the control group. Data represent mean (95% CI) unless indicated.
↵* Significantly higher than the asthma groups.
↵† Significantly lower than the mild group.
↵‡ Significantly higher than the control and no treatment groups.
↵§ Significantly higher than the control group.
BMI, body mass index; FEV1, forced expiratory volume in 1 s; GC, glucocorticoid.