Table 1

Maternal characteristics of the study populations according to asthma treatment and asthma severity

Asthma treatmentAsthma severity
ControlNo treatmentInhaled corticosteroidsp ValueMildModerate–severep Value
n5152715865
Age29.8 (27.4 to 30.9)*25.7 (23 to 27)26.7 (25 to 28)<0.00126.0 (23.4 to 26.8)26.5 (25.0 to 28.0)<0.001
Height (cm)164.2 (162.2 to 165.9)164.1 (161.8 to 166.1)164.0 (162.7 to 165.8)0.99163.4 (162.0 to 166.0)164.4 (162.6 to 165.8)0.81
Weight (early) (kg)73.9 (65.0 to 77.4)76.9 (69.2 to 81.175.3 (69.8 to 81.3)0.8077.4 (68.9 to 80.7)74.7 (70.0 to 81.6)0.67
Weight (late) (kg)83.0 (76.6 to 87.9)88.3 (81.7 to 92.985.4 (80.5 to 91.2)0.4788.1 (82.2 to 92.8)85.3 (80.2 to 91.2)0.47
BMI27.4 (24 to 29)28.3 (26 to 30)27.7 (26 to 30)0.8228.3 (25 to 30)27.7 (26 to 30)0.82
Gravida (median, range)2 (1–10)2 (1–8)2 (1–8)0.112 (1–8)2 (1–8)0.020
Parity (median, range)1 (0–6)*0 (0–4)1 (0–6)0.0110 (0–4)1 (0–6)0.004
FEV13.2 (3.0 to 3.4)3.2 (3.0 to 3.3)3.0 (2.9 to 3.2)0.103.2 (3.0 to 3.4)3.0 (2.8 to 3.2)0.043
Vital capacity3.9 (3.8 to 4.1)3.8 (3.6 to 4.0)3.8 (3.6 to 3.9)0.703.8 (3.6 to 3.9)3.8 (3.6 to 3.9)0.71
GC dose, third trimester001054.2 (890.7 to 1233.2)<0.001234.5 (123.8 to 350.3)§928.0 (705.9 to 1117.5)<0.001
Smoking n (%)3 (5.9%)14 (26.9%)20 (28.2%)0.00612 (20.7%)§22 (33.8%)§0.001
  • Significance values represent a comparison of each asthma treatment and the control group and of each asthma severity and the control group. Data represent mean (95% CI) unless indicated.

  • * Significantly higher than the asthma groups.

  • Significantly lower than the mild group.

  • Significantly higher than the control and no treatment groups.

  • § Significantly higher than the control group.

  • BMI, body mass index; FEV1, forced expiratory volume in 1 s; GC, glucocorticoid.