Study group | Number | Males/females | AAT (mg/ml) mean (SD) | CRP (mg/ml) mean (SD) | TIMP-1 (ng/ml) mean (SD) | ||||||
Total | Males | Females | Total | Males | Females | Total | Males | Females | |||
MM | 84 | 29/55 | 1.28 (0.36) | 1.22 (0.3) | 1.32 (0.3) | 2.12 (3.3) | 1.39 (2.17) | 2.5 (3.7) | 65.3 (38.3) | 59.5 (33.7) | 68.3 (40.4) |
SZ | 22 | 12/10 | 0.601*** (0.11) | 0.58 (0.09) | 0.64 (0.13) | 1.4 (2.2) | 1.82 (2.7) | 0.92 (1.24) | 99.4* (55.1) | 113.5 (69.1) | 82.4 (25.6) |
ZZ | 50 | 31/19 | 0.225*** (0.08) | 0.23 (0.06) | 0.23 (0.11) | 2.1 (2.2) | 2.56 (2.56) | 1.99 (1.6) | 136.4*** (75.2) | 150.4 (84.9) | 112.1 (53.9) |
*p<0.05 and ***p<0.001 show significant difference between ZZ or SZ AAT deficiency and controls with the normal MM genotype of AAT.