Budesonide (mg)* | Salbutamol (mg)* | ||||
Correlation | p Value† | Correlation | p Value† | ||
Infant lung function | |||||
Abnormal‡ | 0.375 | 0.007 | 0.445 | 0.001 | Mann–Whitney U test |
sGaw (Z-score) | −0.168 | 0.243 | −0.170 | 0.239 | Spearman test |
FRC (Z-score) | 0.026 | 0.856 | 0.137 | 0.343 | Spearman test |
Infant skin prick test positive | −0.051 | 0.727 | −0.107 | 0.461 | Mann–Whitney U test |
Infant bronchial biopsy | |||||
RBM (mm) | 0.406 | 0.003 | 0.201 | 0.162 | Spearman test |
Mast cells | 0.378 | 0.018 | 0.228 | 0.163 | Spearman test |
Symptoms during infancy | |||||
Frequent wheeze | 0.300 | 0.034 | 0.121 | 0.402 | Mann–Whitney U test |
Wheeze between colds | 0.102 | 0.482 | 0.125 | 0.388 | Mann–Whitney U test |
Bold denotes p<0.05.
↵* Purchase of inhaled budesonide or salbutamol during third year of life expressed in mg.
↵† Z-test for Spearman correlation coefficient but, if one of the variables is dichotomous, the Mann–Whitney U test was used.
↵‡ Abnormal LF defined as reduced LF (sGaw Z-score <−1.65).
FRC, functional residual capacity; RBM, reticular basement membrane; sGaw, specific airway conductance.