Table 1

Patient characteristics at the start and completion of antibiotic treatment for an exacerbation and when stable

Start of IV antibioticsCompletion of IV antibioticsStable
Mean (SD) (n=26)Mean (SD)Mean difference from start* (95% CI) (n=26)p ValueMean (SD)Mean difference from start* (95% CI) (n=13)p Value
Weight (kg)59.25 (10.70)59.09 (10.93)−0.16 (−0.48 to 0.17)0.3359.27 (12.92)+0.28 (−0.05 to 0.60)0.09
FEV1 (l)1.65 (0.76)2.05 (0.84)+0.39 (0.21 to 0.58)<0.0011.71 (0.66)+0.12 (−0.05 to 0.30)0.16
CRP (mg/l)*11.7 (3.8–28.8)7.4 (3.5–14.5)−7.6 (−2.0 to −21.5)0.00513.0 (2.8–33.5)+0.5 (−33.5 to 15.8)0.91
WCC (×109/l)*10.1 (8.1–14.2)7.2 (6.0–10.3)−2.5 (−4.7 to −0.8)0.0112.5 (10.2–16.1)+1.9 (−3.7 to +4.5)0.58
  • * As CRP and WCC are skewed, the median and IQR are presented along with the median difference from start (95% CI) and the p value from the Wilcoxon signed rank test.

  • CRP, C reactive protein; FEV1, forced expiratory volume in 1 s; IV, intravenous; WCC, white cell count.