Table 1

Functional and clinical outcomes following omalizumab therapy

PretreatmentPost-treatmentp
FEV1 (ml)1360 (955–2200)1850 (1270–2290)0.08
FEV1 (% predicted)66% (39–73)74% (70–84)0.03
Annual rate of exacerbations1 (1–4)0 (0–1)0.01
Daily symptoms (≥2 times per week)15/18 patients (83%)8/18 patients (44%)0.04
Nocturnal symptoms (≥2 times per week)15/18 patients (83%)4/18 patients (22%)0.04
Oral corticosteroids17/18 patients (94%)6/18 patients (33%)0.0005
Itraconazole10/18 patients (55%)3/18 patients (16%)0.037
  • Results are expressed as median with range in brackets or as a percentage. The Wilcoxon test was used to evaluate any significant differences (p<0.05) between continuous variables and the χ2 test was employed for comparison of categorical variables.