Table 3

Environmental tobacco smoke (ETS) exposure from the mother at different time points* and personal smoking as risk factors for asthma and wheeze at age 16–17 years

Physician-diagnosed asthmaEver wheezeCurrent wheeze
OR95% CIOR95% CIOR95% CI
Model AIn utero exposure1.220.94 to 1.591.050.85 to 1.301.160.93 to 1.45
Daily smoking1.330.91 to 1.941.871.39 to 2.521.971.46 to 2.67
ETS at age 7–8 years1.301.02 to 1.671.261.03 to 1.541.190.97 to 1.47
Daily smoking1.320.90 to 1.931.881.40 to 2.531.961.45 to 2.66
ETS at age 16–17 years1.250.96 to 1.631.210.98 to 1.501.150.92 to 1.45
Daily smoking1.360.93 to 1.981.891.41 to 2.551.991.47 to 2.70
Continuous ETS1.471.09 to 1.991.341.04 to 1.711.180.91 to 1.54
Daily smoking1.350.93 to 1.961.871.39 to 2.501.991.47 to 2.68
Model BIn utero exposure1.220.82 to 1.821.050.85 to 1.301.160.93 to 1.45
1–10 cigarettes/day1.220.82 to 1.821.751.29 to 2.381.761.29 to 2.42
≥11 cigarettes/day1.380.69 to 2.721.941.12 to 3.372.441.41 to 4.22
ETS at age 7–8 years1.311.02 to 1.681.261.03 to 1.541.190.97 to 1.47
1–10 cigarettes/day1.180.78 to 1.771.681.23 to 2.291.741.26 to 2.39
≥11 cigarettes/day1.320.67 to 2.621.981.15 to 3.412.341.35 to 4.05
ETS at age 16–17 years1.260.96 to 1.641.210.98 to 1.511.150.92 to 1.44
1–10 cigarettes/day1.220.81 to 1.821.701.24 to 2.311.771.29 to 2.44
≥11 cigarettes/day1.330.67 to 2.631.961.14 to 3.862.351.35 to 4.07
Continuous ETS1.481.10 to 2.001.341.04 to 1.721.190.91 to 1.55
1–10 cigarettes/day1.960.80 to 1.781.721.27 to 2.341.741.27 to 2.38
≥11 cigarettes/day1.470.76 to 2.822.031.19 to 3.462.421.42 to 4.15
  • ORs were calculated by multiple logistic regression analyses, adjusting for sex, family history of asthma, current place of residence, house dampness and birth weight <2500 g.

  • * The variables regarding ETS from the mother were included one at a time.