Table 3

Decline in lung function per year by 11478G→A genotype in Whitehall II and ELSA cohorts

Whitehall II (n=2721)ELSA (n=1805)
GG (wild type)−4 (−8 to −1)−36 (−44 to −29)
GA−14 (−23 to −5)−23 (−49 to −11)
AA−76 (−127 to −26)−60 (−166 to −37)
p Value (for trend)0.0030.720
  • ELSA, English Longitudinal Study of Ageing.

  • Data are expressed as geometric mean (and 95% CI) change in forced expiratory volume in 1 s (ml/year), adjusted for age, sex and smoking status.