Table 2

Protein identifications in bronchoalveolar lavage fluid exosomes by mass spectrometry of bands (10, 20 and 50 kDa) appearing stronger in patients with sarcoidosis by silver staining

NameAccession codeCorresponding cut bandMass (kDa)Function
Ig γ-1 chain C regionP0185750 kDa, 20 kDa, 10 kDa36106Interact with protein or protein complex
PHD finger protein 12Q96QT650 kDa109699Chromatin-mediated gene regulation
Zink finger protein 749O4336150 kDa80607Regulate expression of genes and nucleic acid recognition, reverse transcription and virus assembly
Pro-neuregilin-1, membrane-bound isoform precursorQ0229720 kDa70392Growth and differentiation of epithelial, glial, neuronal and skeletal muscle cells; inducing expression of acetylcholine receptor; stimulating lobuloalveolar budding and milk production and inducing differentiation of mammary tumour cells
U4/U2 small nuclear ribonucleoprotein Prp31Q8WWY320 kDa55457Pre-mRNA splicing