Abstract P125 Table 1

 

No prior LABD treatmentPrior LABD treatment
All
T+OTT+OT
Baseline characteristics
n426454603579
Age (years), mean ± SD62.7 ± 8.362.6 ± 8.864.6 ± 8.364.8 ± 8.2
Male, n (%)291 (68.3)338 (74.4)442 (73.3)417 (72.0)
Ex-smoker, n (%)241 (56.6)278 (61.2)388 (64.3)385 (66.5)
Post-bronchodilator FEV1 (L), mean ± SD1.38 ± 0.521.43 ± 0.541.32 (0.50)1.32 (0.51)
Post-bronchodilator FEV1 (% predicted), mean ± SD50.7 ± 16.050.8 ± 15.748.3 ± 14.748.8 ± 15.6
Reversibility (mL), mean ± SD158 ± 160166 ± 144169 ± 138174 ± 147
Lung function after 24 weeks of treatment
Adjusted mean FEV1 AUC0–3, (mL) ± SE270 ± 1154 ± 9256 ± 8150 ± 8
Adjusted mean trough FEV1 (mL) ± SE148 ± 172 ± 1134 ± 886 ± 8
GOLD 2
T+OTT+OT
Baseline characteristics
n228240274277
Age (years), mean ± SD63.0 ± 8.262.5 ± 8.965.3 ± 8.964.8 ± 8.7
Male, n (%)148 (64.9)160 (66.7)202 (73.7)180 (65.0)
Ex-smoker, n (%)117 (51.3)128 (53.3)176 (64.2)179 (64.6)
Post-bronchodilator FEV1 (L), mean ± SD1.72 ± 0.441.77 (0.47)1.69 (0.44)1.69 (0.45)
Post-bronchodilator FEV1 (% predicted), mean ± SD63.2 ± 8.863.1 ± 8.462.0 ± 7.462.7 ± 8.1
Reversibility (mL), mean ± SD175 ± 156184 ± 163201 ± 151196 ± 170
Lung function after 24 weeks of treatment
Adjusted mean FEV1 AUC0–3, (mL) ± SE289 ± 13175 ± 13302 ± (12)179 ± 12
Adjusted mean trough FEV1 (mL) ± SE146 ± 1468 ± 14156 ± 1395 ± 13
  • SD, standard deviation; SE, standard error.