Results of spirometry in the subgroup with physician-diagnosed COPD (n=123)
| Men (n=52) | Women (n=71) | All (n=123) | p Value* | |
|---|---|---|---|---|
| Actual median (IQR) | ||||
| FEV1 | 1.4 (1.1–1.8) | 1.0 (0.7–1.1) | 1.1 (0.8–1.4) | <0.001† |
| FVC | 2.4 (2.0–3.1) | 1.6 (1.3–1.9) | 1.9 (1.5–2.3) | <0.001† |
| FEV1/FVC | 0.6 (0.5–0.7) | 0.6 (0.5–0.7) | 0.6 (0.5–0.7) | 0.591† |
| PEF | 382.5 (243–519) | 218 (144–290) | 259 (191–380) | <0.001† |
| %predicted median (IQR) | ||||
| FEV1 | 63.5 (50.9–73.4) | 64.2 (51.7–79.9) | 64.2 (51.3–76.4) | 0.609† |
| FVC | 77.4 (64.2–94.1) | 87.6 (70.4–101.0) | 82.8 (68.2–99.8) | 0.040† |
| Spirometry %(N) | ||||
| Normal | 7.7 (4) | 8.5 (6) | 8.1 (10) | 0.959‡ |
| Restrictive | 15.4 (8) | 16.9 (12) | 16.3 (20) | |
| Obstructive | 76.9 (40) | 74.7 (53) | 75.6 (93) | |
| Obstructive spirometry§ %(N) | ||||
| Mild | 10.0 (4) | 20.8 (11) | 16.1 (15) | 0.190¶ |
| Moderate | 60.0 (24) | 56.6 (30) | 58.1 (54) | |
| Severe | 27.5 (11) | 20.8 (11) | 23.7 (22) | |
| Very severe | 2.5 (1) | 1.9 (1) | 2.2 (2) | |
| FEV1 %(N) | ||||
| Below LLN | 48.1 (25) | 33.8 (24) | 39.8 (49) | 0.137** |
| Normal range | 51.9 (27) | 66.2 (47) | 60.2 (74) | |
| Above ULN | 0.0 (0) | 0.0 (0) | 0.0 (0) | |
| FEV1 Z-score | ||||
| median (IQR) | 1.6 (1.2–2.2) | 1.3 (0.7–2.0) | 1.5 (0.9–2.0) | 0.039† |
| FVC %(N) | ||||
| Below LLN | 30.8 (16) | 14.1 (10) | 21.1 (26) | 0.043** |
| Normal range | 69.2 (36) | 84.5 (60) | 78.1 (96) | |
| Above ULN | 0.0 (0) | 1.4 (1) | 0.8 (1) | |
| FVC Z-score | ||||
| median (IQR) | 1.1 (0.3–1.8) | 0.6 (0.0–1.2) | 0.8 (0.0–1.6) | 0.008† |
| Oxygen saturation | ||||
| median (IQR) | 97 (96–98) | 97 (95–98) | 97 (95–98) | 0.521† |
*Comparison of men and women.
†Mann–Whitney U test.
‡χ2 test.
§This is based on the 93 participant subsample with obstructive spirometry.
¶Kruskal–Wallis test.
**Fisher's exact test.
LLN, lower limit of normal; PEF, peak expiratory flow; ULN, upper limit of normal.